Clinical Research Directory

Inclusion criteria: * Age 45-80 years * Patients diagnosed with knee osteoarthritis according to American College of Rheumatology criteria and presenting with Kellgren-Lawrence grade 2 or 3 radiological osteoarthritis * Intact cognitive function * INR ≤1.2 * Willingness to participate in the study and sign informed consent forms Exclusion criteria: * Presence of neurological and/or vestibular disease causing balance impairment * Physical therapy for knee osteoarthritis within the last 6 months * Glucocorticoid or hyaluronic acid injection within the last 6 months * Use of oral glucosamine * History of knee surgery * Existing neurological or mental disorders * History of pacemaker use * Local infections or sepsis * Progressive neurological deficit * Oncological diseases * History of systemic inflammatory diseases such as rheumatoid arthritis * Clinically significant structural abnormalities-in addition to osteoarthritis-that affect movement and knee function and could cause chronic knee pain * Bleeding diathesis or INR \>1.2 * Uncontrolled diabetes or other serious internal comorbidities * Allergy to the medication or materials used * Pregnancy * Lack of cooperation * Refusal to participate in the study