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Comparison of Topical Antibiotics Versus Systemic Antibiotics in Preventing Burn Wound Infection in Pediatric Burn Patients
Sponsor: abdul mateen
Summary
Burn wound infection is a common complication in children with burns and can delay healing and increase the risk of complications. This randomized controlled trial will compare two antibiotic strategies for preventing infection in pediatric burn patients. One group will receive topical antibiotics alone, while the other group will receive topical antibiotics along with systemic antibiotics. The study will compare the occurrence of burn wound infection between the two groups to determine whether adding systemic antibiotics provides additional benefit in preventing infection.
Key Details
Gender
All
Age Range
5 Years - 13 Years
Study Type
INTERVENTIONAL
Enrollment
222
Start Date
2026-11-05
Completion Date
2027-05-05
Last Updated
2026-10-13
Healthy Volunteers
No
Conditions
Interventions
Silver Sulfadiazine Cream 1%
Silver sulfadiazine 1% cream applied once daily to the burn wound according to the departmental protocol
Amoxicillin and clavulanate
Amoxicillin plus clavulanate at a total dose of 50 mg/kg/day, administered three times daily according to the departmental protocol.
Locations (1)
King Edward Medical University
Lahore, Punjab Province, Pakistan