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NOT YET RECRUITING
NCT07870967
NA

Undenatured Type II Collagen for Knee Osteoarthritis Pain

Sponsor: Universidad Católica San Antonio de Murcia

View on ClinicalTrials.gov

Summary

This randomized, controlled, double-blind, three-arm parallel clinical trial will evaluate the efficacy and safety of undenatured type II collagen products on joint pain in adults diagnosed with knee osteoarthritis. Participants will be randomized to Nuvicol II, Nuvicol SII, or placebo and will consume one capsule daily for 4 months. Pain, quality of life, knee muscle function, concomitant analgesic medication use, cartilage degradation biomarkers, safety laboratory variables, and adverse events will be assessed during follow-up.

Official title: Randomized Clinical Trial to Analyze the Efficacy and Safety of Undenatured Type II Collagen Product on Joint Pain in Patients Diagnosed With Osteoarthritis

Key Details

Gender

All

Age Range

31 Years - Any

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2027-03

Completion Date

2027-07

Last Updated

2026-10-13

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Placebo

Matching placebo capsules containing maltodextrin and magnesium stearate, orally once daily for 4 months.

DIETARY_SUPPLEMENT

Nuvicol II

Undenatured type II collagen from chicken source, 40 mg orally once daily for 4 months.

DIETARY_SUPPLEMENT

Nuvicol SII

Undenatured type II collagen from salmon source, 40 mg orally once daily for 4 months.

Locations (1)

UCAM HiTech - Unidad de Estudios Clínicos

Murcia, Murcia, Spain