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Phasix Mesh Underlay During Loop Ileostomy Closure
Sponsor: Corewell Health West
Summary
This prospective study will evaluate whether placement of long-acting absorbable Phasix mesh during loop ileostomy closure reduces the development of an incisional hernia at the ileostomy closure site in patients with a BMI greater than 25. Participants will undergo mesh-reinforced closure and will be followed for two years after surgery. The primary outcome is development of an incisional hernia at the ileostomy closure site, confirmed by CT imaging at two years.
Official title: Phasix Mesh Underlay During Loop Ileostomy Closure: A Single Center Prospective Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
65
Start Date
2026-10-30
Completion Date
2028-10-30
Last Updated
2026-10-13
Healthy Volunteers
No
Interventions
Long-acting absorbable mesh
Lon-acting absorbable Phasix mesh is placed in the retro-rectus space during loop ileostomy closure to reinforce the closure site. The posterior rectus sheath is closed prior to mesh placement, and the mesh is not fixated to surrounding tissue. If the posterior rectus sheath is not intact or cannot be closed, mesh-reinforced closure is not performed and standard primary closure with suture is used.
Locations (1)
Corewell Health West
Grand Rapids, Michigan, United States