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COMPLETED
NCT07871786
PHASE4

Efficacy of a Sonic Toothbrush and 8% Arginine Toothpaste in Reducing Dentinal Hypersensitivity

Sponsor: Colgate Palmolive

View on ClinicalTrials.gov

Summary

This clinical study evaluates the efficacy of an oral hygiene regimen consisting of an electric sonic toothbrush used in combination with an 8.0% arginine and calcium carbonate toothpaste in reducing dentinal hypersensitivity compared to a manual soft-bristled toothbrush with the same desensitizing toothpaste. Adult participants with tactile/air-blast hypersensitive teeth brush twice daily for 7 days. Sensitivity reductions are evaluated at baseline, immediately post-brushing, at 3 days, and at 7 days.

Official title: Clinical Investigation to Assess the Efficacy of a Sonic Toothbrush and a Toothpaste Containing 8.0% Arginine and Calcium Carbonate in Reducing Dentinal Hypersensitivity

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2021-12-06

Completion Date

2022-02-14

Last Updated

2026-10-13

Healthy Volunteers

No

Interventions

DRUG

8.0% Arginine Dentifrice

Commercial fluoride toothpaste containing 8.0% arginine and calcium carbonate.

DEVICE

Electric Sonic Toothbrush

Commercially available electric sonic toothbrush.

DEVICE

Adult Soft Bristle Manual Toothbrush

Commercially available adult soft bristle manual toothbrush (ADA reference).

Locations (1)

The Federal University of Rio Grande do Sul

Porto Alegre, Rio Grande do Sul, Brazil