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Efficacy of a Sonic Toothbrush and 8% Arginine Toothpaste in Reducing Dentinal Hypersensitivity
Sponsor: Colgate Palmolive
Summary
This clinical study evaluates the efficacy of an oral hygiene regimen consisting of an electric sonic toothbrush used in combination with an 8.0% arginine and calcium carbonate toothpaste in reducing dentinal hypersensitivity compared to a manual soft-bristled toothbrush with the same desensitizing toothpaste. Adult participants with tactile/air-blast hypersensitive teeth brush twice daily for 7 days. Sensitivity reductions are evaluated at baseline, immediately post-brushing, at 3 days, and at 7 days.
Official title: Clinical Investigation to Assess the Efficacy of a Sonic Toothbrush and a Toothpaste Containing 8.0% Arginine and Calcium Carbonate in Reducing Dentinal Hypersensitivity
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2021-12-06
Completion Date
2022-02-14
Last Updated
2026-10-13
Healthy Volunteers
No
Interventions
8.0% Arginine Dentifrice
Commercial fluoride toothpaste containing 8.0% arginine and calcium carbonate.
Electric Sonic Toothbrush
Commercially available electric sonic toothbrush.
Adult Soft Bristle Manual Toothbrush
Commercially available adult soft bristle manual toothbrush (ADA reference).
Locations (1)
The Federal University of Rio Grande do Sul
Porto Alegre, Rio Grande do Sul, Brazil