Inclusion Criteria:
* Age: 18 to 55 years old, both inclusive.
* Gender: Male and/or non-pregnant, non-lactating female. A. Female of child-bearing potential had a negative serum beta human chorionic gonadotropin (β-HCG) pregnancy test performed within 28 days of the first dose of study medication. They used an acceptable form of contraception.For female of child-bearing potential, acceptable forms of contraception included the following:i. Non hormonal intrauterine device in place for at least 3 months prior to the start of the study and remaining in place during the study period, orii. Barrier methods containing or used in conjunction with a spermicidal agent, oriii. Surgical sterilization oriv. Practicing sexual abstinence throughout the course of the study.B. Females were not considered of child-bearing potential if one of the following was reported and documented on the medical history:i. Postmenopausal with spontaneous amenorrhea for at least 12 consecutive months without other medical explanation, orii. Bilateral oophorectomy with or without a hysterectomy and an absence of bleeding for at least 6 months, oriii. Total hysterectomy and an absence of bleeding for at least 3 months.
* 18.5 to 30.0 kg/m2, both inclusive; BMI values were rounded off to one significant digit after decimal point (e.g. 30.04 rounded down to 30.0, while 18.45 rounded up to 18.5).
* Able to communicate effectively with study personnel.
* Non-alcoholic, non-smoker and non-tobacco user (i.e. had no past history of drinking alcohol, smoking and tobacco consuming for at least one year prior tostudy).
* Normal or clinically non-significant ECG recording during screening.
* Willing to provide written informed consent to participate in the study.
* All participants were judged by the principal or sub-investigator or physician as normal and healthy during a pre-study safety assessment performed within 28 daysof the first dose of study medication which included:a) A physical examination (clinical examination) with no clinically significantfinding.
Exclusion Criteria:
* History of allergic responses to Empagliflozin, Linagliptin, Metformin or other related drugs, or any of its formulation ingredients.
* Had significant diseases or clinically significant abnormal findings during screening \[medical history, physical examination (clinical examination), laboratory evaluations, ECG recording, gynecological history and examination (including pelvic examination and routine breast examination) (for female participants)\].
* Any disease or condition like diabetes, psychosis or others, which compromised the haemopoietic, gastrointestinal, renal, hepatic, cardiovascular, respiratory, Central nervous system or any other body system.
* History or presence of bronchial asthma.
* Used any hormone replacement therapy within 3 months prior to the first dose of study medication.
* Used any depot injection or implant of any drug within 3 months prior to the first dose of study medication.
* Used CYP enzyme inhibitors or inducers within 30 days prior to the first dose of study medication (see https://drug-interactions.medicine.iu.edu/MainTable.aspx).
* History or evidence of drug dependence.
* History of difficulty with donating blood or difficulty in accessibility of veins.
* A positive hepatitis screen (included subtypes B \& C).
* A positive test result for HIV antibody.
* Participant who had received a known investigational drug within seven elimination half-life of the administered drug prior to the first dose of study medication.
* Participant who had donated blood or loss of blood 50 ml to 100 ml within 30 days or 101 ml to 200 ml within 60 days or \>200 ml within 90 days (excluding volume drawn at screening for this study) prior to first dose of study medication, whichever was greater.
* History of difficulty in swallowing or of any gastrointestinal disease, which affected drug absorption.
* Intolerance to venipuncture.
* Any food allergy, intolerance, restriction or special diet that, in the opinion of the principal investigator or sub-investigator, could contraindicate the participant's participation in this study.
* Institutionalized participant.
* Used any prescribed medications within 14 days prior to the first dose of study medication.
* Used any OTC products, vitamin and herbal products, etc., within 7 days prior to the first dose of study medication.
* Used grapefruit and grapefruit containing products within 7 days prior to the first dose of study medication.
* Ingested any caffeine or xanthine products (i.e. coffee, tea, chocolate, and caffeinecontaining sodas, colas, etc.), recreational drugs within 48 hours prior to the first dose of study medication.
* Ingested any unusual diet, for whatever reason (e.g.: low sodium) for three weeks prior to the first dose of study medication.
* Presence of ketone during urine analysis.
* History or presence of cardiovascular disorders.
* Participant with Serum Lactate higher than upper limit of normal range.
* Participant with Estimated Glomerular Filtration Rate was less than 60 ml/min/1.73 m2 during screening.
* History or presence of hypoglycemia.
* Participant with Serum Creatinine higher than upper limit of normal range.
* History of acute and chronic metabolic acidosis.
* History or sign and symptoms of pancreatitis.
* History of genital mycotic infections.
* History of severe and disabling arthralgia.
* History of bullous pemphigoid.
* History of recurrent urinary tract infection
