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Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic Surgery
Sponsor: Udayana University
Summary
Before surgery, patients are asked to fast so the stomach is empty and stomach contents cannot enter the lungs during anesthesia. Long fasting is uncomfortable and can raise blood sugar and stress responses in older adults. Giving a carbohydrate drink up to 2 hours before surgery is part of enhanced recovery (ERAS) programs. It is not clear whether a maltodextrin drink or sugar water leaves less fluid in the stomach of older patients. This randomized, double-blind study enrolls patients aged 60 years and older who are having elective lower limb orthopedic surgery under spinal or epidural anesthesia at Prof. Ngoerah General Hospital in Denpasar, Indonesia. Participants are assigned by chance to drink 400 mL of either a maltodextrin carbohydrate drink or sugar water 2 hours before anesthesia. The amount of fluid in the stomach is measured with bedside ultrasound before the drink and 2 hours after it. Blood glucose is measured before the drink, 2 hours after it and 6 hours after surgery. The neutrophil-lymphocyte ratio, a blood marker of inflammatory stress, is compared before surgery and 6 hours after surgery. The results are intended to show which drink is better suited to older surgical patients and to support safer and more comfortable fasting practice.
Official title: Comparison of Maltodextrin and Sugar Water Carbohydrate Loading on Gastric Volume in Geriatric Patients Undergoing Lower Extremity Orthopedic Surgery
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2026-09-27
Completion Date
2026-11-30
Last Updated
2026-10-14
Healthy Volunteers
No
Interventions
Maltodextrin carbohydrate drink
400 mL (4 x 100 mL) of ready-to-drink clear maltodextrin beverage (Maltodex, PT Finusoprima Farma Internasional). Per 100 mL: 50 kcal, 13 g carbohydrate of which 4 g sugars, 15 mg sodium, vitamin A and zinc at 15% of daily value each. Single dose, drunk within 15 to 30 minutes, 2 hours before anesthesia. Unlike the comparator it contains added vitamin A and zinc.
Sugar water
400 mL of clear solution prepared by the hospital nutrition installation by dissolving about 50 g of sucrose (table sugar) in drinking water to a final volume of 400 mL (about 200 kcal, no fat, no protein). Single dose, drunk within 15 to 30 minutes, 2 hours before anesthesia.
Locations (1)
Prof. Dr. I.G.N.G. Ngoerah General Hospital (RSUP Prof. Dr. I.G.N.G. Ngoerah)
Denpasar, Bali, Indonesia