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Artificial Intelligence-assisted Primary Care for Influenza Vaccination Among Chronic Patients in China (AIPC-Flu)
Sponsor: Fudan University
Summary
The goal of this clinical trial is to evaluate whether an AI-assisted primary care intervention can increase influenza vaccination uptake among patients with chronic diseases and to assess the cost-effectiveness and potential for implementing the intervention in routine primary care. The main questions it aims to answer are: 1. Does the AI-assisted primary care intervention increase influenza risk perception, influenza vaccine literacy, vaccine confidence, intention to receive influenza vaccination, and influenza vaccination uptake among patients with chronic diseases? 2. Is the AI-assisted primary care intervention cost-effective compared with conventional health education? 3. Is the AI-assisted primary care intervention acceptable, feasible, and potentially sustainable for influenza vaccination promotion? Researchers will compare patients with chronic diseases who receive the AI-assisted primary care intervention with those who do not receive it to determine whether the intervention improves patients' literacy, confidence, intention, and uptake of influenza vaccination. Participants will: 1. Be recruited and randomly assigned to the intervention group or control group. Participants in the intervention group will have access to an AI assistant for influenza vaccine-related information and will receive an influenza vaccination recommendation from primary care physicians, while participants in the control group will receive routine health education. 2. Complete a survey questionnaire assessing patients' influenza risk perception, influenza vaccine literacy, vaccine confidence, and intention to receive influenza vaccination. 3. Have their influenza vaccination uptake assessed at the end of the trial.
Official title: Artificial Intelligence-assisted Primary Care for Influenza Vaccination Among Chronic Patients in China (AIPC-Flu): a Randomized Trial
Key Details
Gender
All
Age Range
18 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
1300
Start Date
2026-10-06
Completion Date
2027-02
Last Updated
2026-10-14
Healthy Volunteers
No
Conditions
Interventions
AI-assisted primary care intervention
Primary care physicians will provide brief health education to participants on influenza vaccination and will recommend the use of an AI-powered influenza vaccine chatbot for at least 5 minutes. For those who are eligible and express willingness to receive influenza vaccination, primary care physicians will assist with appointment scheduling and vaccination. The AI-powered influenza vaccine chatbot is designed to provide information and health education about influenza vaccination. It is powered by large language models and is trained on an expert-validated knowledge base derived from authoritative sources such as the National Health Commission and China CDC to ensure accuracy. The chatbot engages users in interactive, conversational dialogue to answer questions and address concerns regarding influenza vaccination. It is delivered via WeChat or a web browser for user access and offers both conversational and navigational interaction modes, supporting text and voice input.