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NCT07874906

Clinical Comparison of Lithium Disilicate and 3D-Printed Resin Endocrowns

Sponsor: Medipol University

View on ClinicalTrials.gov

Summary

This randomized controlled clinical trial aims to compare the clinical performance of CAD/CAM lithium disilicate (IPS e.max CAD) and 3D-printed resin (BEGO VarseoSmile TriniQ) endocrown restorations in endodontically treated posterior teeth. Eligible patients requiring indirect restorations of two posterior teeth will receive both types of endocrown restorations using a randomized design. All restorations will be fabricated using standardized digital workflows and adhesive cementation protocols. Clinical evaluations will be performed at one week, six months, and one year following restoration placement. The functional, esthetic, and biological properties of the restorations will be assessed according to the World Dental Federation (FDI) criteria. Periapical radiographs will be obtained to evaluate endodontic outcomes. The study aims to compare the clinical survival, functional performance, and potential complications of the two restorative materials, including restoration fracture, debonding, and secondary caries.

Official title: Clinical Performance of Lithium Disilicate CAD/CAM and 3D-Printed Resin Endocrowns in Endodontically Treated Posterior Teeth: A Randomized Controlled Clinical Trial

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

Start Date

2025-10-08

Completion Date

2027-02-08

Last Updated

2026-10-15

Healthy Volunteers

Yes

Conditions

Endodontically Treated Teeth Nonvital Teeth Restoration of Endodontically Treated Posterior Teeth

Interventions

DEVICE

IPS e.max CAD Lithium Disilicate Endocrown

Endocrown restorations fabricated from IPS e.max CAD lithium disilicate ceramic blocks using CAD/CAM technology. Digital impressions were obtained using an intraoral scanner (TRIOS 3, 3Shape), and restorations were designed with a standardized cement space of 100 μm. The internal surfaces were conditioned using hydrofluoric acid etching followed by silane application. Restorations were adhesively cemented under rubber dam isolation using a resin-based luting system.

DEVICE

BEGO VarseoSmile TriniQ Resin Endocrown

Endocrown restorations fabricated from BEGO VarseoSmile TriniQ permanent resin using three-dimensional printing technology. Digital impressions were obtained using an intraoral scanner (TRIOS 3, 3Shape), and restorations were designed with a standardized cement space of 100 μm. The internal surfaces were conditioned using airborne-particle abrasion with aluminum oxide particles followed by silane application. Restorations were adhesively cemented under rubber dam isolation using a resin-based luting system.

Inclusion Criteria: * Adults aged 18-65 years. * Patients classified as American Society of Anesthesiologists (ASA) physical status I or II. * Patients requiring an indirect endocrown restoration for at least one endodontically treated posterior tooth. * Endodontically treated posterior teeth with clinically and radiographically satisfactory root canal treatment, without preoperative symptoms or periapical pathology. * Teeth with sufficient remaining tooth structure and appropriate clinical conditions for endocrown restoration. * Presence of intact adjacent and opposing teeth with stable occlusal relationships. * Teeth that can be adequately isolated using a rubber dam, with deep margin elevation performed when necessary. * Good oral hygiene and low to moderate caries risk, as assessed using the Caries Management by Risk Assessment (CAMBRA) system. * Acceptable periodontal health, defined as Periodontal Screening Index (PSI) ≤ 2 and Papillary Bleeding Index (PBI) ≤ 35%. * Patients physically and mentally capable of tolerating the planned dental procedures. * Patients willing to participate in the study and providing written informed consent. Exclusion Criteria: * Patients with uncontrolled systemic diseases, including uncontrolled diabetes mellitus or immunosuppressive conditions. * Pregnant or breastfeeding individuals. * History of drug or alcohol dependence. * Chronic use of anti-inflammatory medications, analgesics, or psychiatric medications. * Known allergies or hypersensitivity to resin-based composite materials, dental ceramics, or other materials used in the restorative procedures. * Presence of active oral pathological conditions. * Active dental caries or untreated periodontal disease, including PSI \> 2 or PBI \> 35%. * Parafunctional habits, including bruxism or clenching. * Inadequate clinical conditions for rubber dam isolation. * Complications during root canal treatment that compromise the eligibility of the tooth for endocrown restoration. * Patients unwilling or unable to provide written informed consent.

Locations (1)

Istanbul Medipol University

Istanbul, Istanbul, Turkey (Türkiye)