Clinical Research Directory

Key Inclusion Criteria: 1. Has a recent onset of neurological deficit attributed to non-cardioembolic focal brain ischemia as described in the protocol 2. Has index event (non-cardioembolic, non-procedural ischemic stroke, or high-risk TIA) within 30 days prior to randomization as described in the protocol 3. Is planned to receive antiplatelet therapy for secondary stroke prevention in line with local guidelines and practice 4. In case of endovascular therapy (mechanical thrombectomy) and/or thrombolysis, randomization can only occur \>24 hours after endovascular therapy or after thrombolysis as described in the protocol Key Exclusion Criteria: 1. Has any active clinical condition requiring chronic outpatient therapeutic anticoagulation including history of atrial fibrillation or flutter and mechanical heart valves requiring anticoagulation 2. Has had strokes due to non-thrombotic causes (eg, bacterial endocarditis, vertebral or carotid artery dissection), caused by procedures (eg, in the setting of coronary artery bypass grafting), or secondary to hypotension 3. Before index stroke, has modified rankin scale (mRS) score \>3 4. Has known intracranial vascular abnormality with high risk for bleeding (treated aneurysm and aneurysm \<5 mm are not exclusionary) Note: Other protocol-defined Inclusion/ Exclusion Criteria apply