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A Clinical Study to Evaluate the Efficacy and Safety of JS212 Monotherapy or Combination Therapy in Recurrent or Metastatic Triple-negative Breast Cancer(TNBC)
Sponsor: Shanghai Junshi Bioscience Co., Ltd.
Summary
This is an phase II study to prelininarily evaluate the efficacy and safety of JS212 mono therapy or combination therapy in patients with recurrent or metastatic TNBC.
Official title: A Phase II Study of JS212 Monotherapy or Combination Therapy With JS207 or JS001 in Recurrent or Metastatic Triple-negative Breast Cancer(TNBC)
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
184
Start Date
2026-10-15
Completion Date
2029-03-05
Last Updated
2026-10-15
Healthy Volunteers
No
Conditions
Interventions
JS212 in combination with JS207
JS212 and JS207 will be administered intravenously on D1, Q3W
JS212 monotherapy
JS212 will be administered intravenously on D1，Q3W
JS212 in combination with JS001
JS212 and JS001 will be administered intravenously on D1, Q3W
Locations (29)
Fujian Cancer Hospital
Fuzhou, Fujian, China
The First Hospital of Lanzhou University
Lanzhou, Gansu, China
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China
Guangdong General Hospital
Guangzhou, Guangdong, China
The Affiliated Cancer Hospital of Guizhou Medical University City: Guiyang
Guiyang, Guizhou, China
The Affiliated Hospital of Guizhou Medical University
Guiyang, Guizhou, China
Affiliated Hospital of Hebei University
Baoding, Hebei, China
Harbin Medical University Cancer Hospital
Harbin, Heilongjiang, China
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
Henan Cancer Hospital
Zhengzhou, Henan, China
Hubei Cancer Hospital
Wuhan, Hubei, China
The First People's Hospital of Changde City
Changde, Hunan, China
Hunan Cancer Hospital
Changsha, Hunan, China
Jiangsu Province Hospital
Nanjing, Jiangsu, China
Nanchang People's Hospital
Nanchang, Jiangxi, China
Jilin Provincial Cancer Hospital
Changchun, Jilin, China
The First Hospital of Jilin University
Changchun, Jilin, China
Shengjing Hospital of China Medical University
Shenyang, Liaoning, China
Cancer Hospital of Dalian University of Technology(Liaoning Cancer Hospital & Institute)
Shenyang, Liaoning, China
Introduction to the First Affiliated Hospital of China Medical University
Shenyang, Liaoning, China
General Hospital of Ningxia Medical University
Yinchuan, Ningxia, China
Cancer Hospital of Shandong First Medical University(Shandong Cancer Institute, Shandong Cancer Hospital)
Jinan, Shandong, China
Affiliated Hospital of Jining Medical University
Jining, Shandong, China
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China
Weifang People's Hospital
Weifang, Shandong, China
Shanxi Cancer Hospital
Taiyuan, Shanxi, China
Sichuan Provincial People's Hospital
Chengdu, Sichuan, China
Mianyang Central Hospital
Mianyang, Sichuan, China
Peking University People's Hospital
Beijing, China