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COMPLETED
NCT07876713
PHASE4

Acetazolamide to Reduce Spinal Fluid Leaks After Spine Surgery.

Sponsor: Ain Shams University

View on ClinicalTrials.gov

Summary

This study aims to evaluate the effectiveness and safety of acetazolamide in helping patients recover from accidental dural tears during spine surgery. Adding acetazolamide to standard post-surgery care is hypothesized to be a safe and effective way to reduce spinal fluid leakage, ease headaches, and speed up recovery.

Official title: Using Acetazolamide Medication to Reduce Spinal Fluid Leaks and Speed Up Recovery After Spine Surgery

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

26

Start Date

2025-04-06

Completion Date

2026-05-01

Last Updated

2026-10-15

Healthy Volunteers

No

Interventions

DRUG

Acetazolamide

250 mg three times daily for 2 weeks

OTHER

Standard Care (in control arm)

Standard postoperative care without acetazolamide

Locations (1)

Ain Shams University Hospitals.

Cairo, Egypt