Clinical Research Directory

Follicular Flushing Versus Direct Aspiration in Transabdominal Oocyte Retrieval

Sponsor: Centrum Clinic IVF Center

Summary

The goal of this observational study is to learn whether rinsing the egg sacs (follicles) during egg collection helps doctors collect more eggs in women with low egg reserve. Participants are unmarried women aged 18 to 42 who are freezing their eggs and who chose to have eggs collected through the abdomen instead of the vagina. Low egg reserve means a blood level of anti-Müllerian hormone (AMH) of 1 ng/mL or lower. The main questions it aims to answer are: Does rinsing the follicles raise the total number of eggs collected? Does rinsing the follicles raise the number of mature eggs that can be frozen? Researchers will compare two egg collection methods, each used routinely at one of two IVF centres in Turkey: Direct aspiration: each follicle is emptied once with a single-channel needle, with no rinsing. Follicular flushing: a double-channel needle is used. If no egg is found after the first try, the follicle is rinsed with warm fluid and emptied again, up to six times. Participants will: Take fertility hormone injections for about 8 to 12 days so that several follicles grow Have their eggs collected through the abdomen under sedation, guided by ultrasound Have their mature eggs frozen for future use

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