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Prehabilitation Before Liver Surgery in Older Adults
Sponsor: Lining Xu
Summary
Many older adults who need liver surgery (hepatectomy) are physically weak before their operation. This can make recovery harder and may lead to more complications after surgery. "Prehabilitation" is a program of exercise and nutrition support that takes place before surgery, with the goal of helping patients get stronger and better prepared. This study is testing whether a preoperative prehabilitation program helps older adults recover better after liver surgery. We want to find out if it reduces complications and helps patients return to their normal activities sooner. We are looking for adults aged 65 and older who are scheduled to have liver surgery. Participants will be assigned by chance to either the prehabilitation program or standard care before surgery. The prehabilitation program includes guided exercise and nutrition advice over several weeks before the operation. If this program works, it could become a routine part of care for older adults preparing for liver surgery, helping them have safer operations and smoother recoveries.
Official title: Preoperative Prehabilitation for Older Adults Undergoing Hepatectomy
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2021-01-01
Completion Date
2027-12
Last Updated
2026-10-16
Healthy Volunteers
No
Interventions
Preoperative Prehabilitation Program
Participants in the prehabilitation group receive a multimodal preoperative program initiated 2-4 weeks before scheduled hepatectomy. The program includes: (1) individualized supervised or home-based exercise training (aerobic and resistance exercises, 3-5 sessions per week); (2) nutritional assessment and counseling with protein supplementation as needed; and (3) psychological support including relaxation techniques and preoperative education. The program is delivered by a multidisciplinary team (physiotherapist, dietitian, and nurse) through weekly in-person or telehealth sessions. Participants also receive an individualized home program. The intervention continues until the day before surgery. This program is in addition to standard preoperative care. The control group receives standard preoperative care alone, without structured exercise, nutritional, or psychological prehabilitation.
Locations (6)
Chinese PLA general hospital
Beijing, Beijing Municipality, China
Shenzhen Bao'an District Songgang People's Hospital
Shenzhen, Guangdong, China
Henan Cancer Hospital
Zhengzhou, Henan, China
Hubei Province Integrated Hospital of Chinese and Western Medicine
Wuhan, Hubei, China
Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China