Clinical Research Directory
Browse clinical research sites, groups, and studies.
Intertransverse Process Block Versus Erector Spinae Plane Block for Pain Relief in Lumbar Spine Surgery
Sponsor: Hanoi Medical University
Summary
The goal of this clinical trial is to learn whether two types of ultrasound-guided nerve block, the intertransverse process block and the erector spinae plane block, reduce pain and the need for opioid pain medicines during and after lumbar spine surgery in adults. It also compares the two blocks with each other. The main questions it aims to answer are: Do patients who receive either nerve block need less morphine in the first 24 hours after surgery than patients who receive only local anesthetic injected at the skin incision? Is there a difference between the two nerve blocks in pain scores, the amount of opioid medicine needed during and after surgery, the time until patients first ask for pain medicine, and side effects? Researchers will compare three groups: an erector spinae plane block group, an intertransverse process block group, and a control group that receives local anesthetic infiltration at the incision site. Participants will: Be randomly assigned to one of the three groups before surgery Receive the nerve block on both sides of the spine with ropivacaine before general anesthesia (block groups), or local anesthetic infiltration along the planned incision after induction of anesthesia (control group) Undergo general anesthesia and lumbar spine surgery following the same standard protocol Use a patient-controlled analgesia pump that delivers morphine on demand for 24 hours after surgery Rate their pain at rest and during movement at set times over the first 24 hours, and be monitored for side effects such as nausea and vomiting
Official title: Comparison of Intraoperative and Postoperative Analgesic Efficacy Between Single-Injection Erector Spinae Plane Block and Intertransverse Process Block in Lumbar Spine Surgery: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2026-03-01
Completion Date
2026-08-31
Last Updated
2026-10-16
Healthy Volunteers
No
Interventions
Erector Spinae Plane Block
Bilateral ultrasound-guided injection of local anesthetic between the erector spinae muscle and the L3 transverse process, performed in the prone position before induction of general anesthesia.
Intertransverse Process Block
Bilateral ultrasound-guided injection of local anesthetic into the intertransverse space between the L2 and L3 transverse processes, anterior to the erector spinae muscle and posterior to the intertransverse ligament complex, performed in the prone position before induction of general anesthesia.
Local anesthetic infiltration
Subcutaneous infiltration along both sides of the planned skin incision by the surgeon after induction of general anesthesia and before skin incision.
Morphine PCA
Intravenous morphine 1 mg/mL via patient-controlled analgesia: 1 mg bolus, 8-minute lockout interval, no background infusion, maximum 15 mg per 4 hours, for 24 hours after surgery.
Locations (1)
Hanoi Medical University
Hanoi, Vietnam