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FAPI PET Imaging in Nonischemic Cardiomyopathy
Sponsor: Peking Union Medical College Hospital
Summary
This study aims to evaluate the clinical value of \[¹⁸F\]AlF-NOTA-FAPI-04 PET/CT for the noninvasive assessment of myocardial fibroblast activation in patients with nonischemic cardiomyopathy. The study will investigate whether \[¹⁸F\]AlF-NOTA-FAPI-04 PET/CT can provide complementary information for disease phenotyping, assessment of treatment response, and prognostic risk stratification in nonischemic cardiomyopathy.
Official title: Mapping Myocardial Fibroblast Activation With FAPI PET Imaging in Nonischemic Cardiomyopathy
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2025-12-02
Completion Date
2028-12-31
Last Updated
2026-10-16
Healthy Volunteers
No
Conditions
Interventions
[¹⁸F]AlF-NOTA-FAPI-04
An I.V. bolus injection of up to 10 millicurie (mCi) \[¹⁸F\]AlF-NOTA-FAPI-04 will be administered, followed by a PET/CT scan.
Locations (1)
Peking Union Medical College Hospital
Beijing, China