Clinical Research Directory

MRI Study of OnabotulinumtoxinA (OnabotA) Effect on Jaw Muscle Pain

Sponsor: Weill Medical College of Cornell University

Summary

The goal of this clinical trial is to learn which magnetic resonance images are best able to assess and predict if a participant with masticatory myofascial pain syndrome will benefit from Botox injections, as compared to placebo (saline, salt water). The main questions the study aims to answer are: * Will diffusion MR images will be best able to assess and predict if a participant with masticatory myofascial pain syndrome will benefit from Botox injections? * Will Botox injections reduce masticatory myofascial pain and improve jaw function?

Official title: MRI-based Comparison of OnabotulinumtoxinA (OnabotA) Versus Placebo Injections to the Temporalis and Masseter Muscles in the Management of Myofascial Pain Syndrome: A Randomized Clinical Trial

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