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Comparison of Ketorolac and Dexmedetomidine as An Adjunct to Lignocaine in Prevention of Tourniquet Induced Pain During Intravenous Regional Anesthesia
Sponsor: Mayo Hospital Lahore
Summary
This study compared ketorolac and dexmedetomidine when added to lignocaine to prevent pain caused by a tourniquet during intravenous regional anesthesia. This technique involved injecting a local anesthetic into a vein to numb an arm or leg for surgery. A tourniquet, a tight cuff placed around the limb, restricted blood flow but could cause pain during the procedure. The study was conducted at Mayo Hospital, Lahore, and was designed to include 70 patients aged 18-60 years undergoing surgery on the lower part of an arm or leg. Two treatment groups of 35 patients each received lignocaine with either dexmedetomidine or ketorolac. Pain was assessed on a scale from 0 to 10 at 15, 30, and 45 minutes after tourniquet application. Additional pain relief was administered when the pain score reached 4 or higher.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2026-02-15
Completion Date
2026-08-15
Last Updated
2026-10-16
Healthy Volunteers
No
Conditions
Interventions
Dexmedetomidine
Dexmedetomidine 0.5 micrograms/kg was administered as an adjunct to lignocaine for prevention of tourniquet-induced pain during intravenous regional anesthesia.
ketorolac
Ketorolac 30 mg was administered as an adjunct to lignocaine for prevention of tourniquet-induced pain during intravenous regional anesthesia.
Lidocaine
Lidocaine 0.5% at 3 mg/kg was administered for intravenous regional anesthesia in both treatment groups.
Locations (1)
Mayo Hospital, Lahore
Lahore, Punjab Province, Pakistan