Clinical Research Directory

Inclusion Criteria: * Individuals with occupational injury or disease claims related to exposure to hazardous chemical substances or other non-solar hazardous agents recorded in the National Insurance Institute of Israel database between January 1, 2018, and December 31, 2025. * Claims classified as occupational substance exposure according to the administrative diagnostic and exposure classification system. * Records containing information relevant to at least one study outcome, including demographic characteristics, clinical diagnoses, disability determinations, assigned disability percentages, or compensation classifications. * Both male and female claimants. * Workers 18 y.o. and higher Exclusion Criteria: * Claims exclusively related to solar radiation, sunlight exposure, or associated actinic conditions. * Occupational claims unrelated to hazardous substance exposure. * Records outside the study period. * Records without sufficient information to establish eligibility for the occupational substance-exposure cohort. * Duplicate administrative records representing the same determination, when identifiable. Separate legitimate claims or determinations relating to the same individual will not automatically be excluded.