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Enhancing the Durability of Thread-Assisted Brow Suspension Through Upper Blepharoplasty-Assisted Ligament Release
Sponsor: Muhammed Mustafa Demirok
Summary
This prospective clinical study aims to investigate whether combining upper blepharoplasty with limited release of the lateral brow-retaining ligaments improves the long-term effectiveness of barbed thread brow suspension. Lateral eyebrow drooping can contribute to an aged or tired appearance around the eyes. Although thread-based brow lifting can improve eyebrow position, the lifting effect may decrease over time. The researchers aim to determine whether releasing the tissue attachments that restrict eyebrow movement can help maintain the lifting effect. The study plans to enroll 90 adults aged 20-70 years, divided into three groups of approximately 30 participants each: 1. Standard upper blepharoplasty alone. 2. Standard barbed thread brow suspension alone. 3. Upper blepharoplasty combined with lateral retaining ligament release and barbed thread brow suspension. Treatment selection will be based on each participant's anatomical characteristics and clinical indications, without random assignment. Participants will be evaluated before surgery and at 1 week and 1, 3, 6, and 12 months after surgery. Standardized photographs will be analyzed to measure changes in lateral eyebrow height. Eyebrow symmetry, complications, adverse events, and the need for revision surgery will also be assessed. The study aims to determine whether the combined surgical approach provides more durable lateral brow elevation without increasing postoperative complications.
Official title: Enhancing the Durability of Thread-Assisted Brow Suspension Through Upper Blepharoplasty-Assisted Retaining Ligament Release: A Hybrid Surgical Approach for Long-Term Brow Elevation
Key Details
Gender
All
Age Range
20 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2026-10-27
Completion Date
2028-01-31
Last Updated
2026-10-16
Healthy Volunteers
No
Interventions
Upper Blepharoplasty
Standard upper blepharoplasty involving excision of excess upper eyelid skin, with management of the orbicularis oculi muscle and orbital fat when clinically indicated. In the hybrid treatment arm, the upper blepharoplasty incision also provides access for limited lateral brow-retaining ligament release.
Barbed Thread Brow Suspension
Lateral brow suspension using CE-marked, double-needle, barbed poly(L-lactide-co-epsilon-caprolactone) (PLACL) threads. The threads are used to elevate and support the lateral eyebrow through fixation to the temporal fascia. The technique is performed either as a standalone brow-lifting procedure or in combination with upper blepharoplasty and lateral retaining ligament release.
Lateral Brow-Retaining Ligament Release
Limited surgical release of the lateral brow-retaining ligaments and associated soft-tissue attachments through an upper blepharoplasty incision. The procedure is performed to facilitate superior mobilization of the lateral eyebrow and reduce tissue resistance before barbed thread suspension. This intervention is performed exclusively in the hybrid treatment arm.
Locations (1)
Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital
Istanbul, Istanbul, Turkey (Türkiye)