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NOT YET RECRUITING
NCT07880730

Right Heart Injury Monitoring on ECMO

Sponsor: Papworth Hospital NHS Foundation Trust

View on ClinicalTrials.gov

Summary

This study aims to find out whether it is practical to introduce a consistent monitoring approach to the right side of the heart in patients supported with VV-ECMO. VV-ECMO is a life support machine that takes over the work of the lungs to give them time to recover. It is used when lung injury is life-threatening. Whilst receiving VV-ECMO support, in addition to the current standard of care, the following will be performed twice weekly: * Heart scan (echocardiogram) * Blood tests (hs-troponin and NT-proBNP) The patient's involvement in the study lasts for as long as they are on the life support machine, plus one final heart scan 48 hours after it is removed.

Official title: Feasibility Study for Monitoring Right Ventricular Injury in Patients With Severe Acute Respiratory Failure Supported With Veno-venous Extracorporeal Membrane Oxygenation

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

30

Start Date

2026-11

Completion Date

2028-01

Last Updated

2026-10-19

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Transthoracic echocardiogram

Transthoracic echocardiogram with a dedicated RV protocol

DIAGNOSTIC_TEST

High sensitivity troponin

Twice weekly measurements

DIAGNOSTIC_TEST

N-terminal pro-B-type natriuretic peptide

Twice weekly measurement.

Locations (1)

Royal Papworth Hospital NHS Foundation Trust

Cambridge, Cambridgeshire, United Kingdom