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A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes
Sponsor: Eli Lilly and Company
Summary
The purpose of this study is to investigate the efficacy and safety of eloralintide and tirzepatide coformulation (EloraTZP) compared with tirzepatide, eloralintide and placebo for body weight reduction in participants with obesity. Participation in the study will last about 2 years.
Official title: A Phase 3 Study to Investigate the Efficacy and Safety of LY900043 in Adult Participants With Obesity Without Type 2 Diabetes
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
2115
Start Date
2026-12
Completion Date
2029-11
Last Updated
2026-10-19
Healthy Volunteers
No
Conditions
Interventions
eloralintide and tirzepatide
Administered SC
Eloralintide
Administered SC
Tirzepatide
Administered SC
Placebo
Administered SC
Locations (155)
Care Access - 801 South Power Road, Mesa
Mesa, Arizona, United States
Headlands Research - Scottsdale
Scottsdale, Arizona, United States
Tucson Clinical Research Institute
Tucson, Arizona, United States
Valley Clinical Trials, Inc.
Covina, California, United States
Los Angeles Institute for Metabolic Research
Los Angeles, California, United States
Peninsula Research Associates
Rolling Hills Estates, California, United States
Artemis Institute for Clinical Research
San Diego, California, United States
Southern California Clinical Research
Santa Ana, California, United States
Yale University School of Medicine
New Haven, Connecticut, United States
JEM Research Institute
Atlantis, Florida, United States
K2 Medical Research - Maitland
Maitland, Florida, United States
Flourish Research - Miami, LLC
Miami, Florida, United States
Care Access - Tamarac
Tamarac, Florida, United States
Care Access - Tampa
Tampa, Florida, United States
Care Access - Dalton Walmart
Dalton, Georgia, United States
Teak Research Consults - Dunwoody
Dunwoody, Georgia, United States
Clinical Research Atlanta
Stockbridge, Georgia, United States
Rophe Adult and Pediatric Medicine/SKYCRNG
Union City, Georgia, United States
East-West Medical Research Institute
Honolulu, Hawaii, United States
IMA Clinical Research Chicago
Chicago, Illinois, United States
DM Clinical Research - Indianapolis
Indianapolis, Indiana, United States
Care Access - Eunice
Eunice, Louisiana, United States
Clinical Trials Management, LLC d/b/a Flourish Research
Metairie, Louisiana, United States
Pharmasite Research, Inc.
Baltimore, Maryland, United States
Care Access - Baltimore
Baltimore, Maryland, United States
Brigham and Women's Hospital Diabetes Program
Boston, Massachusetts, United States
SKY Integrative Medical Center/SKYCRNG
Ridgeland, Mississippi, United States
IMA Clinical Research Las Vegas
Las Vegas, Nevada, United States
Palm Research Center Sunset
Las Vegas, Nevada, United States
IMA Clinical Research Albuquerque
Albuquerque, New Mexico, United States
NYC Research INC
Long Island City, New York, United States
Weill Cornell Medical College
New York, New York, United States
IMA Clinical Research NYC Midtown
New York, New York, United States
University of North Carolina Medical Center
Chapel Hill, North Carolina, United States
Medication Management
Greensboro, North Carolina, United States
Care Access - Raleigh
Raleigh, North Carolina, United States
Clinical Research of Philadelphia
Philadelphia, Pennsylvania, United States
Keystone Clinical Studies
Plymouth Meeting, Pennsylvania, United States
Clinical Neuroscience Solutions Inc.
Memphis, Tennessee, United States
JCCT - Juno Bellaire Site
Bellaire, Texas, United States
The University of Texas Health Science Center at Houston
Bellaire, Texas, United States
Cedar Health Research
Dallas, Texas, United States
Cedar Health Research - Euless
Euless, Texas, United States
Biopharma Informatic, LLC
Houston, Texas, United States
PlanIt Research, LLC
Houston, Texas, United States
Care Access - Houston - Clinical Trials Center by Walmart & Care Access
Houston, Texas, United States
Activian Clinical Research
Kingwood, Texas, United States
Clinical Trials of Texas, LLC
San Antonio, Texas, United States
Consano Clinical Research, LLC
Shavano Park, Texas, United States
Care Access - Tyler - Clinical Trials Center by Walmart & Care Access
Tyler, Texas, United States
Kalo Clinical Research
West Valley City, Utah, United States
Care Access - Arlington 2
Arlington, Virginia, United States
Washington Center for Weight Management and Research
Arlington, Virginia, United States
Health Research of Hampton Roads, Inc.
Newport News, Virginia, United States
Eastern Virginia Medical School (EVMS) Medical Group
Norfolk, Virginia, United States
Instituto de Investigaciones Clínicas Bahia Blanca
Bahía Blanca, Argentina
DOLZ Investigación Clínica
Buenos Aires, Argentina
Cicemo Srl
Buenos Aires, Argentina
Consultorio Medico Investigador Principal Dr Besada
Buenos Aires, Argentina
Centro Médico Viamonte
Buenos Aires, Argentina
Mautalen Salud e Investigación
Buenos Aires, Argentina
CEMEDIC
Buenos Aires, Argentina
Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada
Buenos Aires, Argentina
IDIM - Instituto de Investigaciones Metabólicas
Ciudad de Buenos Aires, Argentina
Centro Medico Privado San Vicente Diabetes
Córdoba, Argentina
MICA - Medicina e Investigación Cardiometabólica
Del Viso, Argentina
Hospital Español de Mendoza
Godoy Cruz, Argentina
Centro de Investigaciones Clínicas Baigorria
Granadero Baigorria, Argentina
CMD-Centro Médico y Diagnóstico por Imágenes
Junín, Argentina
Centro de Investigaciones Médicas Mar del Plata
Mar del Plata, Argentina
Instituto de Cardiología Wolff
Mendoza, Argentina
Instituto Médico Catamarca IMEC
Rosario, Argentina
Instituto Médico Fundación Grupo Colaborativo Rosario Investigación y Prevención Medica
Rosario, Argentina
Centro de Investigaciones Médicas Tucuman
SAN M. de Tucuman, Argentina
Sanatorio Norte
Santiago del Estero, Argentina
Luhe Hospital
Beijing, China
Peking University First Hospital
Beijing, China
Peking University People's Hospital
Beijing, China
The Second Hospital of Jilin University
Changchun, China
The Third Xiangya Hospital of Central South University
Changsha, China
Sichuan Provincial People's Hospital
Chengdu, China
2nd Affiliated Hospital Chongqing Medical Universi
Chongqing, China
Zhujiang Hospital
Guangzhou, China
The First Affiliated Hospital of Jinan University
Guangzhou, China
The Second People's Hospital of Hefei
Hefei, China
Jinan Central Hospital
Jinan, China
The First Affiliated Hospital of Henan University of Science &Technology
Luoyang, China
Affiliated Hospital of Luzhou Medical College
Luzhou, China
Jiangxi Provincial People's Hospital
Nanchang, China
Nanjing First Hospital
Nanjing, China
Jiangsu Province Official Hospital
Nanjing, China
The Second Affiliated Hospital of Nanjing Medical University
Nanjing, China
Nanjing Medical University - Nanjing Jiangning Hospital
Nanjing, China
The First Affiliated Hospital of Nanyang Medical College
Nanyang, China
Ningbo First Hospital
Ningbo, China
The First Hospital of Qinhuangdao
Qinhuangdao Shi, China
Jiading District Central Hospital
Shanghai, China
The First Hospital of Hebei Medical University
Shijiazhuang, China
The First Affiliated Hospital of Soochow University
Suzhou, China
Xianyang Hospital of Yan'an University
Xianyang, China