Clinical Research Directory

Browse clinical research sites, groups, and studies.

1 clinical study listed.

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APOE 4

Tundra lists 1 APOE 4 clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT06682767

A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE)

The study aims to evaluate the safety, feasibility, and preliminary efficacy of the fasting-mimicking diet (FMD) or low-dose daily rapamycin treatment relative to a matched placebo control group when administered over 8 weeks in middle-aged adults at elevated risk for Alzheimer's disease due to the apolipoprotein (APOE) ε4 allele. Participants randomly assigned to the FMD intervention will adhere to FMD for 5-days over three cycles for a period of approximately 8 weeks. Participants randomly assigned to the rapamycin and placebo groups will take 1 mg of rapamycin or a matched placebo pill daily for approximately 8 weeks.

Gender: All

Ages: 45 Years - 65 Years

Updated: 2026-09-16

1 state

Cerebral Blood Flow

APOE 4