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Advanced Ovarian Cancer (Stage III or IV) After Neoadjuvant Chemotherapy

Tundra lists 1 Advanced Ovarian Cancer (Stage III or IV) After Neoadjuvant Chemotherapy clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NCT07678008

Prognostic Value of KELIM Score and Inflammatory Markers in Ovarian Cancer

This is a retrospective observational study to evaluate the integrative prognostic value of inflammatory markers, specifically the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR), alongside the CA-125 Elimination rate constant K (KELIM) score in advanced ovarian cancer patients. The study includes patients with advanced serous ovarian cancer (stage III or IV) who received neoadjuvant platinum-based chemotherapy followed by interval debulking surgery at Sohag University Hospital and Sohag Cancer Center between 2022 and 2025. The primary objective is to evaluate how well these biomarkers predict survival outcomes, including progression-free survival (PFS) and overall survival (OS). Additionally, the study aims to assess their significance in predicting the success of complete versus incomplete cytoreductive surgery following neoadjuvant chemotherapy.

Gender: FEMALE

Ages: 18 Years - Any

Updated: 2026-07-01

Advanced Ovarian Cancer (Stage III or IV) After Neoadjuvant Chemotherapy

High-grade Serous Ovarian Carcinoma