Clinical Research Directory
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4 clinical studies listed.
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Tundra lists 4 Aggressive Fibromatosis clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT03785964
Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)
This study evaluates nirogacestat (PF-03084014) in the treatment of desmoid tumor/aggressive fibromatosis (DT/AF). In the double-blind phase, half of the participants will receive nirogacestat while the other half will receive placebo. Once participants are eligible to roll into the open-label phase, they will receive nirogacestat.
Gender: All
Ages: 18 Years - Any
Updated: 2026-08-20
24 states
NCT07176689
Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)
This study is being conducted to study how nirogacestat may affect the ovarian function of adult premenopausal women with progressing desmoid tumors/aggressive fibromatosis.
Gender: FEMALE
Ages: 18 Years - 40 Years
Updated: 2026-08-17
2 states
NCT07170644
A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)
This study is being conducted to characterize the efficacy and safety of nirogacestat in Japanese adults with progressing desmoid tumors/aggressive fibromatosis.
Gender: All
Ages: 18 Years - Any
Updated: 2026-06-29
2 states
NCT02867033
National Clinical-biological Prospective Cohort of Incident Cases of Aggressive Fibromatosis (ALTITUDES)
The purpose of this study is to constitute the French largest Aggressive fibromatosis cohort.
Gender: All
Updated: 2026-03-30