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Algorithm Validation for Fractional Flow Reserve Derived From Intravascular Ultrasound

Tundra lists 1 Algorithm Validation for Fractional Flow Reserve Derived From Intravascular Ultrasound clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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COMPLETED

NCT07551518

Retrospective Algorithm Validation of IVUS-FFR in Patients

This is a retrospective, single-center study to develop and validate an updated algorithm for computing fractional flow reserve from intravascular ultrasound images (IvusFFR v2.0). The study will use existing intravascular ultrasound (IVUS) images and corresponding invasive fractional flow reserve (FFR) measurements obtained from approximately 100 patients who underwent clinically indicated coronary angiography, IVUS, and FFR assessment at Fuwai Hospital. All data will be anonymized prior to analysis. The primary objective is to assess the diagnostic accuracy of IvusFFR v2.0 in identifying hemodynamically significant coronary stenosis, using wire-based FFR ≤0.80 as the reference standard. This study involves no prospective intervention or additional patient contact.

Gender: All

Ages: 18 Years - Any

Updated: 2026-04-27

1 state

Coronary Artery Disease

Coronary Stenosis

Algorithm Validation for Fractional Flow Reserve Derived From Intravascular Ultrasound