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Anaplastic Astrocytoma, Not Otherwise Specified

Tundra lists 1 Anaplastic Astrocytoma, Not Otherwise Specified clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT03919071

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

This phase II trial studies how well the combination of dabrafenib and trametinib works after radiation therapy in children and young adults with high grade glioma who have a genetic change called BRAF V600 mutation. Radiation therapy uses high energy rays to kill tumor cells and reduce the size of tumors. Dabrafenib and trametinib may stop the growth of tumor cells by blocking BRAF and MEK, respectively, which are enzymes that tumor cells need for their growth. Giving dabrafenib with trametinib after radiation therapy may work better than treatments used in the past in patients with newly-diagnosed BRAF V600-mutant high-grade glioma.

Gender: All

Ages: 3 Years - 25 Years

Updated: 2026-04-09

42 states

Anaplastic Astrocytoma

Anaplastic Astrocytoma, Not Otherwise Specified

Anaplastic Ganglioglioma