Clinical Research Directory

Evaluating the Outcome of Surgical Clip Versus Ligatures in Securing Base of Appendix in Laparoscopic Appendicectomy.

The goal of this clinical trial is to evaluate the outcome of using surgical clip versus ligature to secure the base of appendix during laparoscopic appendicectomy. The main questions it aims to answer are to compare the post op complications. Compare the length of hospital stay and to compare the impact of cost. Researches will compare the use of surgical clip versus a suture ligature. Participants whom agreed to participate will be randomly assigned into group either using surgical clip or suture ligature to be used during the surgery. Vitis outpatient clinic after 1 month for follow up.

Effects of Cartoons and Mobile Games on Preoperative Anxiety and Fear in Children With Appendicitis: An RCT

his study aims to evaluate the effects of cartoon viewing and mobile game playing on preoperative anxiety and fear levels in children aged 7-12 years who are hospitalized for appendicitis surgery. The study is designed as a randomized controlled trial with three groups: a cartoon group, a mobile game group, and a control group receiving routine care. Children in the intervention groups will watch a cartoon or play a mobile game for 10 minutes before surgery. Anxiety and fear levels will be measured using validated scales before and after the intervention. The findings of this study are expected to contribute to atraumatic care practices by providing simple and effective non-pharmacological methods to reduce preoperative anxiety and fear in children.

Precision Antibiotic Dosing for Appendectomy

This research is studying a drug called cefoxitin already approved by the Food and Drug Administration (FDA) to reduce the risk of infection after surgery to remove an appendix. Researchers are studying a large group of people to continue to learn how best to dose antibiotics. This research will compare the current standard treatment which is a single dose prior to surgery to a new method that includes adding another dose of cefoxitin within 30 minutes of starting the surgery. This study will measure cefoxitin concentrations in blood, fat, and appendix tissue samples to compare the standard dosing method to our new method. This information will help us figure out the right dose of this drug to prevent infection after surgery to remove an appendix.