Clinical Research Directory

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Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)

Tundra lists 1 Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder) clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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RECRUITING

NCT06372821

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

This study will assess if drug (NIO752) reduces production of a protein, tau, by the brain. Normally tau maintains the internal skeleton of nerve cells. In Alzheimer's disease (AD) it builds up in the brain, causing damage. Abnormal tau proteins cling to each other forming 'tangles' inside nerve cells, which interfere with how the nerve cells work, and eventually die. This is what causes the symptoms of dementia. It is thought that NIO752 reduces production of tau.

Gender: All

Ages: 21 Years - 80 Years

Updated: 2026-01-27

1 state

Alzheimer Disease

Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)

Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder)