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Burns Involving 20% or More of Body Surface

Tundra lists 1 Burns Involving 20% or More of Body Surface clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT07126574

Evaluating the Accuracy of Multiple Blood Tests to Diagnose Sepsis in Adult Burn Patients

This prospective diagnostic accuracy study evaluates the performance of presepsin and C-reactive protein (CRP) as early biomarkers for suspected sepsis in adult burn patients. From January 2021 to December 2022, 370 patients with ≥20% total body surface area burns admitted to the Burn Intensive Care Unit at Hallym University Hangang Sacred Heart Hospital were screened; 221 met inclusion criteria. At each clinical suspicion of sepsis (≥2 SIRS criteria), venous blood was drawn for simultaneous measurement of presepsin (via chemiluminescent immunoassay) and CRP (via immunoturbidimetric assay). Diagnostic accuracy will be quantified by sensitivity, specificity, positive/negative predictive values, and area under the ROC curve. The goal is to determine whether presepsin outperforms CRP for early sepsis detection in severe burn patients.

Gender: All

Ages: 18 Years - Any

Updated: 2025-08-17

Sepsis - to Reduce Mortality in the Intensive Care Unit

Burns Involving 20% or More of Body Surface