Clinical Research Directory

Browse clinical research sites, groups, and studies.

1 clinical study listed.

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CNS Primary Tumor, Not Otherwise Specified (NOS)

Tundra lists 1 CNS Primary Tumor, Not Otherwise Specified (NOS) clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT03389802

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

This phase I trial studies the side effects and best dose of APX005M in treating younger patients with primary malignant central nervous system tumor that is growing, spreading, or getting worse (progressive), or newly diagnosed diffuse intrinsic pontine glioma. APX005M can trigger activation of B cells, monocytes, and dendritic cells and stimulate cytokine release from lymphocytes and monocytes. APX005M can mediate a direct cytotoxic effect on CD40+ tumor cells.

Gender: All

Ages: 1 Year - 21 Years

Updated: 2026-02-20

10 states

Glioblastoma Multiforme

High-grade Astrocytoma Not Otherwise Specified (NOS)

CNS Primary Tumor, Not Otherwise Specified (NOS)