Clinical Research Directory

AKTIIA OBPM to Assess CPAP Effect on Blood Pressure in Obstructive Sleep Apnea

The goal of this clinical trial is to learn if positive airway pressure (CPAP) therapy works for blood pressure (BP) control in obstructive sleep apnea (OSA) adult patients plus undiagnosed hypertension (HBP), using a cuffless bracelet for continual optical BP monitoring (AKTIIA OBPM). It will also learn if CPAP improves cardiac function in these patients using speckle tracking echocardiography (STE) and to learn about ease of use and patient experience with AKTIIA device and AKTIIA OBPM. The main questions it aims to answer are: * Does CPAP reduce systolic BP (and other BP metrics) in this population? * Does CPAP improve cardiac function in the same population? Researchers will compare BP metrics derived from AKTIIA OBPM and STE metrics in a before and after CPAP therapy to evaluate its therapeutic effect. Participants will: * Take a CPAP titration and telemonitoring program for 12 weeks (from the titration date) * Take an AKTIIA OBPM one week before CPAP and 12 weeks since CPAP titration date * Take a STE test twice, before starting CPAP and 12 weeks after CPAP titration date * Take an online survey about easy of use and patient experience with AKTIIA OBPM device

Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men

The purpose of this study is to investigate the impact of creatine supplementation alone or in combination with a moderate session of physical activity on vascular reactivity and heart hemodynamics in elderly men.