Clinical Research Directory

Central Line-Associated Bloodstream Infection QI Project

This study evaluates a daily electronic health record (EHR) alert designed to reduce unnecessary central venous catheter (CVC) use among hospitalized adults. The alert identifies patients with an active CVC and no documented indication, prompting the first-contact provider to document line necessity. The study compares alert and a secure chat intervention to usual care, with the goal of reducing unnecessary line days and related CLABSI risk.

Compassionate-Use of 4% T-EDTA Lock Solution for Central Venous Lines of Pediatric PN Patients

In this research study we want to learn more about a study drug, tetrasodium sodium EDTA (Kitelock™) for maintaining the patency (blood flow) through a central venous catheter. Catheter occlusions such as blood clots have been shown to increase the risk of central line-associated bloodstream infection (CLABSI). This treatment consists of instilling a daily a dose of a solution , similar to heparin or saline lock flushes, into the catheter when it is not in use. The aim is to prevent CLABSI without increasing complications such as catheter breakage.

Determining the Prevalence of Primary and Secondary Central Line Associated Blood Stream Infection (CLABSI) at the Tertiary Care Hospital

* Review key history and clinical examination findings of cases with CLABSI. * Microbiological diagnosis and Culture sensitivity tests by automated Bact Alert and Vitek2c systems for CLABSI. * Determine antibiotic biogram of each organism isolated * Determine the prevalence of occurrence of Primary or secondary Blood stream infection, causing microorganism, and predisposing factors.