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Clinical Research Directory

Browse clinical research sites, groups, and studies.

6 clinical studies listed.

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Chemo-brain

Tundra lists 6 Chemo-brain clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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RECRUITING

NCT02290834

Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer

This research study evaluates the effect of chemotherapy on cognition (thinking) and the brain in people with breast cancer.

Gender: FEMALE

Ages: 60 Years - Any

Updated: 2026-03-11

1 state

Impaired Cognition
Chemo-brain
Breast Cancer
ACTIVE NOT RECRUITING

NCT05283629

nCCR for Chemotherapy Related Cognitive Impairment Randomized Study

The investigators propose to apply neuroplasticity-based computerized cognitive remediation (nCCR) to treat chemotherapy-related cognitive impairment (CRCI).

Gender: All

Ages: 35 Years - 80 Years

Updated: 2026-01-08

1 state

Chemo-brain
Chemotherapy-Related Cognitive Impairment
RECRUITING

NCT05864274

Improve Cancer-related Cognitive Impairment

Cancer-related cognitive impairment (CRCI), also known as "chemobrain," is the cognitive decline that negatively impacts the majority of cancer patients undergoing chemotherapy, radiation, and/or hormonal treatments. This application focuses on evaluating if using a cognitive mobile training application can decrease the impact of CRCI in gynecologic oncology patients through a multidisciplinary approach with patients undergoing assessments by our neurocognitive team.

Gender: FEMALE

Ages: 18 Years - 90 Years

Updated: 2025-11-24

1 state

Gynecologic Cancer
Chemotherapy Effect
Chemo-brain
+1
RECRUITING

NCT05014399

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute. This information will be used to identify helpful tests to diagnose individuals at risk for developing difficulties with thinking and memory due to their cancer treatments.

Gender: All

Ages: 18 Years - Any

Updated: 2025-06-11

1 state

Neoplasm, Colorectal
Cognitive Impairment
Cognitive Dysfunction
+5
RECRUITING

NCT05840575

Investigating Cognitive Impairment in Young Patients With Cancer Prospectively

The MyBrain study investigates the brain function of children, adolescents and young adults during and after chemo treatment for cancer. The tests include 1) cognitive skills such as memory and attention; 2) the brain's electrical activity; 3) and biological markers related to brain function. The aim of the study is to better understand the trajectories of cognitive functioning and measures that have been associated with cognitive impairment in patients treated with chemotherapy.

Gender: All

Ages: 7 Years - 29 Years

Updated: 2023-05-03

Chemotherapy-Related Cognitive Impairment
Chemotherapeutic Toxicity
Chemo-brain
+7
RECRUITING

NCT05305092

Assessment of Brain Cognitive Impairment in Breast Cancer

To explore the cognitive impairment caused by chemotherapy and endocrine therapy in premenopausal breast cancer patients and to find biomarkers with early predictive effect on this cognitive impairment by using multimodal integrated PET/MRI technology combined with psychobehavioral technology.

Gender: FEMALE

Updated: 2022-07-13

1 state

Breast Cancer
Chemo-brain
Endocrine Therapy