Clinical Research Directory

Accuracy Comparison: Optoelectronic Motion Capture and Markerless System

The purpose of this study was to assess the Openpose reliability to measure kinematics and spatiotemporal gait parameters and to evaluate the minimum technical requirements. This analysis used video and optoelectronic motion capture simultaneously recorded. We assessed more of 20 subject with different motor gait impairments

TEAMS R34 #1 After-Action Reviews in Child Welfare Services

This project proposes to improve successful mental health service linkage in Child Welfare Services (CWS) by adapting and testing the After Action Review (AAR) team effectiveness intervention to augment the Child Family Team (CFT) services intervention. Despite being both required and a collaborative approach to service planning, CFT meetings are implemented with questionable fidelity and consistency, rarely including children and families as intended. By inclusion of child and family voice, the AAR-enhanced CFT should lead to increased fidelity to the CFT intervention and greater levels of parental satisfaction with the service and shared decision-making, thus resulting in enhanced follow-through with Action Plans and linkage to mental health care for children.

Effects of Battle Rope Training on ROM and Pain in Children With Post Traumatic Elbow Contractures.

The primary objective of this study is to assess the effectiveness of battle rope training in improving ROM, reducing pain, and enhancing overall elbow function in children with post-traumatic elbow contracture. By comparing standard therapy alone to standard therapy plus battle rope training, the study aims to determine if this added intervention leads to greater improvements in functional mobility and pain relief.In this randomized controlled trial, participants will be divided into two groups: a control group, receiving standard treatment (ROM exercises, stretching, and heat therapy), and an intervention group, receiving the same standard treatment plus battle rope training. ROM exercises and stretching will focus on gentle elbow flexion and extension to enhance flexibility, while heat therapy will prepare muscles for movement. The intervention group will additionally perform 10-15 minutes of battle rope training, involving dynamic movements that engage the upper body and increase joint activation. Pre- and post-intervention assessments using a goniometer for ROM, the Flynn scoring system for functional and cosmetic outcomes, and the Visual Analogue Scale (VAS) for pain will provide comprehensive data on the effectiveness of the intervention

Agility and Sprint Performance in Youth Soccer: A Comparison of FIFA 11+ and RAMP Protocols

This randomized clinical trial investigates the comparative effects of the FIFA 11+ and RAMP (Raise, Activate, Mobilize, Potentiate) warm-up protocols on the agility and sprint performance of young soccer players. The study involves 34 male players aged 8 to 15, who will be randomly assigned to one of the two warm-up groups for a six-week intervention period. Key performance outcomes-agility, measured by the Illinois Agility Test, and sprint speed, measured by a 30-meter sprint test-will be assessed both before and after the intervention. The research aims to address a gap in sports science by directly comparing these two popular protocols in a youth population, with the goal of providing coaches with clear, evidence-based recommendations for optimizing athlete development and reducing injury risk. Data will be analyzed through SPSS version 27.00.

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

OPTIC is a prospective, open-label, non-randomized study of multiple medications administered to approximately 2000 children in the pediatric cardiac intensive care unit (PCICU) per routine clinical car by their treating provider. The purpose of this study is to characterize the PK of drugs routinely administered to children per standard of care using opportunistic and scavenged samples. The prescribing of drugs to children will not be part of this protocol. After the child/adult (\<21 years of age) is consented/enrolled, demographic and clinical data will be extracted from the EHR. Biospecimen information (including date and time of sample collection) will be collected. Data analysis will be conducted on all participants with at least 2 evaluable samples. The protocol represents minimal risk to the children/adults who provide body fluid for this study, including potential loss of confidentiality (samples will be assigned a unique accession number) and risks associated with blood draws. Adverse Events (AEs)/Serious Adverse Events (SAEs) caused by the study specimen collections will be monitored and recorded in the Electronic Data Capture (EDC) system.