Clinical Research Directory

Art-Based Emotion Regulation Program

Adolescents receiving cancer treatment often experience increased anxiety, difficulties in emotion regulation, and a high symptom burden due to treatment-related physical effects and psychosocial stressors. Supportive, non-pharmacological interventions that promote emotional regulation are therefore needed. The purpose of this randomized controlled trial is to evaluate the effect of an art-based emotion regulation program on anxiety levels, emotion regulation skills, and symptom burden in adolescents undergoing cancer treatment. This single-blind, parallel-group randomized controlled study will include 60 adolescents aged 10-18 years receiving cancer treatment at Gazi University Health Application and Research Center and Etlik City Hospital Pediatric Hematology-Oncology units between January 30, 2026 and March 20, 2027. Participants will be randomly assigned to either the intervention group or the control group. The intervention group will receive a 4-week art-based emotion regulation program, while the control group will receive routine care. Outcomes will be assessed using validated self-report measures at baseline and at the end of the intervention period.

Four Life Domains Vision Board Program

This randomized controlled trial aims to evaluate the effect of a Four Life Domains-Based Vision Board Program on hope and psychological resilience among adolescents undergoing cancer treatment. Adolescents receiving cancer treatment often experience psychological distress that may negatively affect their sense of hope and resilience. Vision board-based psychosocial interventions grounded in positive psychology and creative expression may support adaptive coping and emotional well-being. The study will be conducted in pediatric hematology-oncology units of Gazi University Health Application and Research Center and Etlik City Hospital in Türkiye. A total of 60 adolescents aged 12-18 years who have been receiving cancer treatment for at least six months will be randomly assigned to either the intervention group (n=30) or the control group (n=30). Participants in the intervention group will receive a structured 5-week Four Life Domains-Based Vision Board Program, consisting of four core modules and one reinforcement session, while the control group will receive standard hospital care only. Outcome measures, including hope and psychological resilience, will be assessed at baseline and after completion of the intervention. The findings are expected to contribute to the development of innovative and holistic psychosocial support interventions for adolescents undergoing cancer treatment.

Using Mukbang to Improve Appetite, Nutritional Status and Quality of Life in Children With Cancer

This study aims to use a two arms randomized clinical trial study to evaluate the effectiveness of the effective constituent of Mukbang in helping children with cancer hospitalized for radiotherapy and chemotherapy to improve their appetite, nutritional status and quality of life.

Evaluation of the Effect of a Physical Activity Recovery Stay

A WHO study in 2020 revealed that 81% of adolescents (aged 11-17) do not respect the recommendation of one hour of moderate physical activity per day. In the context of disability, many factors impose limits on physical activity. While the pathology itself induces limitations and restrictions (prolonged sitting time, assisted movement, etc.), organizational constraints also apply to both children and parents, who have to divide their time between work, school and therapeutic care, which is sometimes numerous and varied over the course of a single week. These limitations generate stress and fatigue, and prolonged sedentary periods lead children with chronic illnesses, rare diseases or disabilities into a process of physical deconditioning. The accumulation of sedentary time is detrimental to cardiovascular and metabolic health. To combat this deconditioning, the 2008 National Physical Activity and Sport Plan (PNAPS) sets out the main guidelines for treatment and implementation. The plan explains that "for patients with chronic illnesses, rare diseases or disabilities, the aim is to encourage care and guidance towards Adapted Physical Activity (APA). The attending physician will be able to identify local therapeutic education programs, rehabilitation services and "sport-santé" offers, to improve access for these patients to supervised local programs". In addition, the plan suggests "developing APA programs in healthcare establishments to enable people with chronic illnesses, rare diseases or disabilities to access health education incorporating practical sessions". In line with this plan, an exercise reconditioning program has been set up at our facility. This three-month stay includes children with a variety of pathologies, but with a common feature of physical deconditioning.