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Clinical Research Directory

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6 clinical studies listed.

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Chronic Non-specific Low Back Pain

Tundra lists 6 Chronic Non-specific Low Back Pain clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ENROLLING BY INVITATION

NCT07286630

Prevalence Of Disability And Fear Avoidance Beliefs

Three hundred eighty -one egyptian physical therapists of both genders with age 25-55 years old in Cairo governorate who have worked for at least two years.The study will be conducted to investigate the prevalence of disability and fear avoidance beliefs among egyptian physical therapists with chronic non-specific low back pain (CNSLBP), and data will be collected through self-administered questionnaires distributed electronically.Participants were recruited from various public and private physical therapy centers and hospitals in Cairo .

Gender: All

Ages: 25 Years - 55 Years

Updated: 2026-03-13

Chronic Non-specific Low Back Pain
ACTIVE NOT RECRUITING

NCT07202533

Pain Neuroscience Education and Exercise for Chronic Nonspecific Low Back Pain

This study aims to evaluate the effects of adding Pain Neuroscience Education (PNE) to motor control exercises in individuals with chronic non-specific low back pain (CNSLBP) who also present with central sensitization. The study focuses on changes in pain intensity, pain-related factors, trunk muscle activation, gait, functionality, kinesiophobia, and quality of life.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2026-02-20

1 state

Chronic Non-specific Low Back Pain
RECRUITING

NCT07296653

Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP)

Chronic non-specific low back pain (CNSLBP) is among the most prevalent causes of disability on the planet, which often proves to be refractory to conventional pharmacological, interventional, and rehabilitation approaches. Although acupuncture has also shown analgesic effectiveness, its variability and reliance on practitioner skill limit its universal introduction into Western medical practice. Prolotherapy, an emerging regenerative injection treatment with hypertonic dextrose solutions, has been of potential benefit in managing musculoskeletal pain by triggering tissue repair and controlling neurogenic inflammation. Interestingly, several acupuncture points correspond to neuroanatomically relevant sites. This single-blind randomized controlled trial aims to ascertain whether combinational prolotherapy with dextrose 15% and lidocaine 1% is superior to lidocaine 1% in patients with CNSLBP. Sixty patients will be allocated randomly into two equal-sized groups and receive a maximum of 15 ultrasound-guided injections into standardized acupoints of the lumbar area (BL23, BL25, BL31, BL54, GV3, GV4, and Ashi points) during three treatment sessions. Outcomes will be evaluated using the Numeric Rating Scale (NRS), the Oswestry Disability Index (ODI), the TUG (Timed Up and Go) test, the BPI (Brief Pain Inventory) scale, the Rolland-Morris Low Back Pain Disability Questionnaire and the Global Impression of Pain Questionnaire at baseline, and at 15, 30, and 90 days post-treatment. Outcomes should clarify whether dextrose-enhanced prolotherapy provides improved analgesia and functional return in comparison with local anesthetic injection alone. This study can present an uncomplicated, low-cost, and integrative regimen for CNSLBP with significant clinical and socioeconomic implications.

Gender: All

Ages: 35 Years - Any

Updated: 2025-12-22

1 state

Chronic Non-specific Low Back Pain
RECRUITING

NCT05832918

Effects of Core Stability Exercises and Cognitive Tasks on Chronic Non-specific Back Pain

This randomized control trial study aims to compare the effect of core stability exercises and cognitive tasks with general exercises and cognitive tasks on pain, disability, and postural control strategies of chronic non-specific low back pain patients. The main questions are: 1. Are core stability exercises and cognitive tasks more effective than general exercises and cognitive tasks in reducing the pain of chronic non-specific low back pain patients? 2. Are core stability exercises and cognitive tasks more effective than general exercises and cognitive tasks in reducing the disability of chronic non-specific low back pain patients? 3. Are core stability exercises and cognitive tasks more effective than general exercises and cognitive tasks in improving postural stability parameters of chronic non-specific low back pain patients? 4. Are core stability exercises and cognitive tasks more effective than general exercises and cognitive tasks in improving stabilogram diffusion analysis parameters of chronic non-specific low back pain patients? This study is designed to apply two exercise protocols on two groups of 17 people with non-specific back pain. Group A will receive core stability exercises along with cognitive tasks, and group B will receive general exercises along with cognitive tasks.

Gender: All

Ages: 18 Years - 55 Years

Updated: 2025-05-07

1 state

Chronic Non-specific Low Back Pain
NOT YET RECRUITING

NCT06903091

Efficacy of Text-messaging on Activity Limitation in People With Chronic Low Back

The main aim of this study was to evaluate the medium-term efficacy of an intervention involving personalized, automated text messaging (SMS), following face-to-face rehabilitation sessions, on activity limitation in people with chronic low back pain. We hypothesize that personalized SMS follow-up, following face-to-face rehabilitation sessions, could reduce activity limitation in people with chronic low back pain. Prospective multicenter randomized controlled trial. Participants in both groups, experimental and comparator will have 4 face-to-face multidisciplinary rehabilitation sessions. Participants in the 2 groups will have a face-to-face medical-kinesthetic clinical consultation at M3. Participants in the experimental group will be monitored by personalized SMS messages over 6 months.

Gender: All

Ages: 18 Years - 70 Years

Updated: 2025-04-18

1 state

Chronic Non-specific Low Back Pain
RECRUITING

NCT06856642

Comparison of Abdominal Draw-in Maneuver With Real-time Ultrasound Imaging Biofeedback vs Conservative Physical Therapy in Patients With Chronic Low Back Pain

The aim of this study is to compare the effectiveness of abdominal drawing-in maneuver with real-time ultrasound biofeedback to conservative treatment in patients with chronic nonspecific low back pain.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2025-03-06

Chronic Non-specific Low Back Pain