Clinical Research Directory

Pre-procedural Risk Score-Based Endoscopist Assignment for Pain Reduction in Unsedated Colonoscopy

This multicenter randomized controlled trial evaluates whether a pre-procedural risk score-based endoscopist assignment strategy reduces intraprocedural pain in high-risk patients undergoing unsedated colonoscopy. High-risk patients (risk score \>5) are randomized 1:1 to either the intervention group (examination performed by expert endoscopists with ≥5,000 colonoscopy experiences) or the control group (examination performed by endoscopists assigned per routine hospital scheduling). The primary outcome is the proportion of patients reporting moderate-to-severe pain during colonoscopy, assessed by a blinded research assistant using a 4-point VRS. A total of 106 high-risk patients will be enrolled from two centers in China.

Effect of Foot Bath After Colonoscopy

This randomized controlled trial evaluated whether a 30-minute foot bath with warm water (40-41°C) after colonoscopy reduces post-procedure pain and abdominal distension and shortens the time to first passage of flatus. Ninety adults undergoing planned colonoscopy were randomized to a foot bath group or standard care. Pain and distension were assessed using a visual analog scale at 0, 15, and 30 minutes after the procedure. Time to first flatus and overall satisfaction were also recorded.