Clinical Research Directory
Browse clinical research sites, groups, and studies.
3 clinical studies listed.
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Tundra lists 3 DFNB9 clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT05402813
Natural History in Children up to 16 Years With Mild to Profound Hearing Loss Due to Mutations in GJB2 / OTOF Genes
The purpose of this study is to follow the natural history of non-syndromic hearing loss caused by mutations in two genes (GJB2 or OTOF) in children up to 16 years of age.
Gender: All
Ages: Any - 16 Years
Updated: 2026-04-06
NCT06722170
A Study of EH002 Gene Therapy for Otoferlin Gene Mutation-mediated Hearing Loss
The study is designed to evaluate the safety, tolerability, and preliminary efficacy of EH002 for the treatment of congenital deafness caused by mutations in the OTOF gene. Participants may receive one or two injections of the EH002 gene therapy in one or both ears.
Gender: All
Ages: 6 Months - Any
Updated: 2025-07-25
2 states
NCT06370351
A Phase I/II Clinical Trial with SENS-501 in Children Suffering from Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations
This study intends to assess safety, tolerability, and efficacy of SENS-501 in children between the ages of 6-31 months with pre-lingual hearing loss due to a mutation in the Otoferlin gene.
Gender: All
Ages: 6 Months - 31 Months
Updated: 2024-09-26