Clinical Research Directory

Effects of Kinesio Tape on Delayed Onset Muscle Soreness

The purpose of this study is to determine the effect of Kinesio tape on delayed onset muscle soreness of the biceps muscle of your arm following strenuous exercise of the bicep muscle.

Antioxidant Supplementation and Muscle Recovery From DOMS in Trained Women

This randomized, placebo-controlled, parallel-group trial investigated the effects of combined antioxidant and anti-inflammatory supplementation on delayed onset muscle soreness (DOMS) recovery in trained women. Sixty trained women (18-35 years) were randomized into four groups: G1 (Creatine + Omega-3), G2 (Creatine + Omega-3 + NAC), G3 (Creatine + Omega-3 + NAC + CoQ10), and G4 (Placebo). Outcomes included muscle pain pressure threshold, countermovement jump, handgrip strength, 30-meter sprint, bilateral dynamometry, infrared thermography, creatine kinase, and heart rate variability, assessed before and after an eccentric exercise protocol.

Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise

The goal of this clinical trial is to learn whether wearing mineral-infused clothing helps muscles recover after a hard bout of unaccustomed exercise in healthy adults aged 18 to 45 who have not done lower-body resistance or jump training in the last 6 months. The main question it aims to answer is: does wearing the mineral-infused garment lead to greater recovery of leg muscle strength (maximal voluntary isometric contraction of the knee extensors) 72 hours after exercise, compared with wearing an identical garment without the mineral infusion? Researchers will also compare the two garments for recovery of jump performance, muscle soreness and blood creatine kinase (a marker of muscle damage), and will describe garment comfort and tolerability. Participants will: * Complete electronic consent, an online screening questionnaire and a video screening call * Attend the study site on four consecutive days * On Day 1, complete baseline tests, then perform 100 drop jumps (5 sets of 20) to cause muscle soreness * Wear their allocated garment for at least 16 hours a day (day and overnight) for the following 72 hours and keep a daily wear log * Have strength, jump and soreness tests and a finger-prick blood sample at each visit (24, 48 and 72 hours after exercise)

Effects of Allicin Pretreatment on Anti-oxidation Ability and Delayed Onset Muscle Soreness

To investigate the effects of allicin pretreatment on delayed onset muscle soreness (DOMS), muscle function, and oxidative stress following eccentric exercise

"Recovery Techniques on Pain, Force and Muscle Oxygenation in Athletes: A Crossover Trial"

The goal of this clinical trial is to evaluate the impact of various passive post-exercise recovery techniques on professional athletes. The main questions it aims to answer are: Do passive recovery modalities significantly improve muscle oxygenation and tissue temperature immediately following high-intensity effort? Which specific technique is most effective in reducing perceived pain, measured by the pressure pain threshold, and restoring muscle strength? Researchers will compare six different therapeutic interventions-Transfer of Energy Capacitive and Resistive therapy, manual massage, intermittent negative pressure therapy, extracorporeal shockwave therapy, percussion therapy, and pneumatic pressotherapy-to determine which provides a superior immediate physiological and functional recovery effect. Participants will: Perform a high-intensity physical effort designed to induce peripheral fatigue. Be randomly assigned to receive one of the six recovery protocols. Undergo objective measurements immediately after the intervention, including near-infrared spectroscopy to assess muscle oxygen saturation, tissue thermography, algometry, and dynamometry.

Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery

Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS). Blood flow restriction relies on applying pressurized cuffs to the most proximal portion of the limb. Another form of recovery often relied upon is pneumatic compression. The mechanism by which pneumatic compression works is similar to that of a massage, whereby the device progressively increases the pressure on a portion of the limb before releasing and moving further up the limb.The purpose of this study is determine whether BFR or pneumatic compression can be used to decreased DOMS which may indicate enhanced recovery.

Delayed Onset Muscle Soreness of Athletes

Study Design: This study was approved by the Human Experiment Ethics Committee of Chengdu Sport University (No: 2103). Based on previous research data, G-power software was used to calculate that at least 40 samples were needed. Participants: A total of 45 track and field athletes from Sichuan Province, China, were recruited during the off-season in 2024. They were randomly assigned to the vibration group, kinesio taping group, combined group, and control group. All participants signed informed consent forms and adhered to the Declaration of Helsinki. DOMS Modeling: Following previous research, a delayed onset muscle soreness (DOMS) model for athletes\' knee joints was established through downhill running. Detailed oxygen uptake tests were conducted on all participants one week before DOMS modeling, and records were made one week after DOMS modeling. Intervention Measures: The vibration group received vibration training immediately after DOMS modeling. The kinesio taping group had Y-shaped kinesio taping applied 30 minutes before DOMS modeling. The combined group received both vibration training and kinesio taping simultaneously. Assessment Methods: The degree of pain at the DOMS site for participants was evaluated using a Visual Analogue Scale (VAS). The concentration of creatine kinase (CK) in the serum of participants was detected using an RT-9600 automatic biochemical analyzer, and serum interleukin-6 (IL-6) was detected by enzyme-linked immunosorbent assay (ELISA). An IsoMed 2000 isokinetic tester was used to perform a 60°/s extension test on the participants\' knees. Data Collection: VAS scores, serum CK and IL-6 levels, and peak torque of knee extension were collected at different time points before and after DOMS modeling.