Clinical Research Directory

The Effect of Mindfulness in Inflammation Markers (IL-6, TNF-A, CRP and Cortisol) Among Survivors of Tidal Flooding in Sayung Demak

Recurrent tidal flooding (rob) in the coastal areas of Sayung District, Demak Regency, poses a continuous environmental threat that inflicts housing damage, economic instability, and prolonged socioeconomic uncertainty on local residents. These chronic stressors frequently trigger significant psychological distress, including elevated levels of stress, anxiety, and depression, while simultaneously activating systemic inflammatory pathways and dysregulating the hypothalamic-pituitary-adrenal (HPA) axis. Mindfulness body scan is a structured, non-pharmacological mind-body technique that involves directing non-judgmental attention to physical sensations across the body. Within a psycho-neuro-immunological framework, mindfulness practice is hypothesized to reduce physiological stress responses, promote autonomic nervous system balance, and downregulate pro-inflammatory pathways. This randomized controlled trial evaluates the effectiveness of a structured 8-day mindfulness body scan intervention on both biological inflammatory markers and psychological outcomes among tidal flood survivors. Participants recruited from Sayung 1 Primary Health Center will be randomly allocated into two groups: 1. Intervention Group: Receives structured 8-day Mindfulness Body Scan training. 2. Control Group: Receives standard health monitoring. All participants will undergo baseline and post-intervention assessments, which include venous blood sampling to analyze key inflammatory and stress biomarkers-Interleukin-6 (IL-6), Tumor Necrosis Factor-alpha (TNF-α), C-Reactive Protein (CRP), and Cortisol. In addition, psychometric instruments will evaluate changes in depression, anxiety, stress, sleep quality, and overall quality of life. The primary objective is to determine whether a short-term mindfulness body scan practice can effectively reduce systemic inflammation and improve post-disaster psychological well-being in coastal communities.

Effect of the MERCI Model in Gamified Disaster Midwifery Education

Midwives play important societal roles during the post-crisis transition and recovery phase. Specific guidelines regarding the roles and responsibilities of midwives, who constitute a significant majority among healthcare professionals, in disaster management need to be developed, and the concept of disaster midwifery needs to be developed. Providing midwife candidates with disaster awareness throughout their undergraduate education will also positively impact individuals' self-efficacy. In recent years, educational plans for emergency obstetric care and management have evolved from traditional theoretical and clinical training to game-based learning, gamification, and training using mannequins and simulators. It is suggested that using different learning strategies in the training of healthcare professionals in emergency obstetric situations will improve the quality of care and reduce maternal mortality rates. Natural disasters such as disasters can cause serious obstetric emergencies requiring immediate intervention and management. Supporting the professional training of midwives, who play important roles and responsibilities in disaster management, with diverse teaching strategies is crucial for enhancing their individual competencies. This study was planned to investigate the effects of gamified disaster midwifery education on midwifery students' knowledge, self-efficacy in disaster response, and levels of self-confidence and anxiety in clinical decision-making. This experimental study, designed with a randomized pretest, posttest, and follow-up design and a control group, will be conducted with third- and fourth-year midwifery students in the Department of Midwifery at the Health Sciences University (SBU), Hamidiye Faculty of Health Sciences (HSBF), during the spring semester of the 2025-2026 academic year. The sample size was determined using Koca and Arkan's study. Based on a Cohen's d = 1.35 effect size and a power level of 95%, a total of 90 participants were planned, with 45 students in each group. The intervention group will receive a 4-week gamified disaster midwifery training featuring core task cycles, interactive digital escape room games, and bonus tasks. The control group will receive case-based learning on the same subject. Participants included in the study will be administered the "Informed Consent Form," "Introductory Information Form," "Disaster Midwifery Information Form," "Disaster Intervention Self-Efficacy Scale," "Self-Confidence and Anxiety Scale in Clinical Decision Making," and "Gamified Disaster Midwifery Experience Form". Discussions and conclusions of the study will be written based on the findings.

Physiotherapy and Disaster

The purpose of this observational study is to examine the relationships between disaster response self-efficacy, psychological preparedness for disaster threats, and interdisciplinary readiness levels among undergraduate Physiotherapy and Rehabilitation students. The study will be conducted among students studying in the Physiotherapy and Rehabilitation departments of Pamukkale University, İnönü University, and Alanya Alaaddin Keykubat University in Turkey. Participants will complete online surveys regarding disaster preparedness while continuing their routine education as part of their active learning. No clinical practice, medical intervention, or experimental procedures will be conducted in the study. The primary research question of this study is: Is there a significant relationship between the disaster response self-efficacy, psychological preparedness, and interdisciplinary readiness levels of physiotherapy students? Data will be collected voluntarily via Google Form; students can withdraw from the study at any time. Personal information will not be collected, and all data will be analyzed solely for scientific purposes, in accordance with confidentiality principles. While no medical or physical benefits are expected for participants, the findings are expected to contribute to the development of physiotherapy training curricula for disaster preparedness and crisis management. The study will commence in December 2025 following ethics committee approval, and the entire process, including data collection, is planned to take approximately six months.

DV 100 as a Framework for the Hospital Incident Command System

There is limited scientific research on the organizational structure of the Hospital Incident Command System. The Hospital Alarm and Emergency Planning manual by the German Federal Office of Civil Protection and Disaster Assistance (BBK) recommends a continental staff system-based organization, as outlined in the Service Regulation DV 100, similar to military, fire, and police structures. This approach is frequently discussed at professional conferences, but evidence on its functionality in hospitals is lacking. This study aims to generate new insights into the use of a continental staff system-based Hospital Incident Command System and qualitatively analyze transition and communication processes within the command structure.