Clinical Research Directory

Physiotherapy and Osteopathic Treatment for Pain in the Cervical and Lumbar Spine and Temporomandibular Joints

Study Summary: Effectiveness of Physiotherapy and Osteopathy in Treating Spinal and Temporomandibular Joint Pain About the Study and Its Objective This study is conducted by Artur Hołodniuk, MSc, a physiotherapist and academic lecturer. The primary goal of the project is to evaluate the effectiveness of various manual and physical techniques in treating pain in the spine (cervical and lumbar regions) and the temporomandibular joints (TMJ). The therapy aims to reduce muscle tension, improve mobility, and alleviate symptoms associated with conditions such as discopathy or degenerative changes. Who Can Benefit from Participation? The project is addressed to individuals struggling with: pain and stiffness in the neck and lower back, pain in the masseter and temporal muscles, limited jaw mobility, as well as headaches and gluteal pain, tension resulting from a sedentary lifestyle or physical strain. Phase One: Comprehensive Diagnostics Before therapy begins, each participant undergoes a series of modern and safe measurements for a multi-dimensional health analysis: Myotomy: An objective assessment of selected muscle tension. Stabilometric Platform: Analysis of body posture and balance control. Jaw Grip Strength: Checking the functional performance of the stomatognathic system. Diaphragm Research Belt: Evaluating respiratory and stabilizing functions of the diaphragm. Fukuda Test: Assessing vestibular function and spatial orientation. Questionnaires: Standardized tools to determine pain intensity, sleep quality, and the impact of symptoms on daily life. Phase Two: Applied Treatment Methods The study utilizes six main forms of support, tailored individually to the patient's needs: General Osteopathic Treatment (GOT): A holistic manual approach involving gentle joint mobilizations and soft tissue work to restore the body's functional balance and range of motion. Visceral Therapy: Precise, gentle manual work with the internal organs of the chest and abdomen to improve their mobility and reduce tensions transmitted to the spine. Pulsed Magnetic Field: 30-minute treatments using low-frequency fields to achieve analgesic, anti-inflammatory, and edema-reducing effects. Positional Placement: Adopting specifically selected body positions using bolsters or pillows to offload painful structures and promote relaxation. External Stabilization: The use of a cervical collar or lumbar corset for temporary stabilization and offloading of the spine, protecting tissues while preventing secondary muscle weakness. Safety and Contraindications All applied techniques are non-invasive. Before starting, the therapist conducts a detailed interview to exclude contraindications, such as: acute inflammation, infections with fever, fresh injuries, or fractures, active cancer or advanced osteoporosis, electronic implants like pacemakers (specifically for magnetic field therapy), high-risk pregnancy. Possible Reactions: Following therapy, temporary reactions may occur, such as fatigue, tissue tenderness, sleepiness, or a short-term increase in pain, which typically subside quickly. Important Information for Participants Voluntary Participation: Participation is entirely voluntary. You may withdraw at any stage without providing a reason. Insurance: Participants are covered by appropriate civil liability insurance for the duration of the study. Privacy: Personal data (name, age, weight) is protected and used solely for identification purposes within the research project. Contact Information Individuals interested in participating or seeking further clarification may contact the lead researcher directly: Phone: 796 947 765 E-mail: arturholodniuk@o2.pl

Intradiscal rhGDF-6 for the Treatment of Lumbar Disc Degeneration

The goal of this clinical trial is to find out if a new medicine can help people who have long-lasting back pain caused by damaged spinal discs. The study will also check if the medicine is safe to use. The main questions this study aims to answer are: Is the medicine safe, and what amount works best? Can it reduce long-term back pain? Researchers will test a medicine called CBT005, which contains a healing protein, by injecting it into the spinal discs. They will watch closely to see how people respond to the treatment. Participants will: Receive one study injection into the spinal disc Visit the clinic in person during the first 12 months for checkups Receive phone calls at 24 and 36 months to see how they are doing Still be able to get other pain treatments in the future, including surgery, if needed