Clinical Research Directory

Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope

The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected or diagnosed endometrial polyps or retained products of conception up to 2.5 cm in size. The main questions it aims to answer are: * Which demographic, gynecologic, clinical, and hysteroscopic factors are associated with successful completion of office operative hysteroscopy using a mini-resectoscope without anesthesia? * Which factors are associated with severe pain during the procedure, defined as a Visual Analog Scale (VAS) score greater than 7? * Is prolonged procedure duration (\>3 minutes) associated with higher intraoperative pain scores? * Are there differences in success rates between procedures performed for endometrial polyps versus retained products of conception? Participants will: * Undergo office operative hysteroscopy without anesthesia using the Miniresectoscope device for removal of endometrial polyps or retained products of conception. * Provide demographic, obstetric, gynecologic, and medical history information before the procedure. * Have intraoperative hysteroscopic and surgical characteristics recorded, including cervical stenosis, uterine orientation, lesion size and location, lesion morphology, and procedure duration. * Complete pain assessments using the Visual Analog Scale (VAS) during the procedure and 5 minutes after the procedure. * Be evaluated for procedural success, defined as complete removal of the intrauterine pathology.

Evaluation of the Uterine Cavity After Operative Hysteroscopy

This study will focus on evaluation of the uterine cavity after operative hysteroscopy using three dimensional transvaginal ultrasonography and office hysteroscopy to detect and residual or recurrent abnormalities or intrauterine adhesions to optimize the results of operative hysteroscopy in different uterine pathologies such as uterine polyps, fibroids, adhesions in addition to mullerian anomalies especially uterine septum .

The Effect of Levonorgestrel Intrauterine System in Preventing Endometrial Polyps Recurrence

The goal of this clinical trial is to determine whether the LNG-IUS is more effective to that of expectant in preventing endometrial polyp recurrence after hysteroscopic polypectomy. Researchers will compare LNG-IUS to expectant management to see if LNG-IUS works to reduce the recurrence rate of endometrial polyps. Participants will: Receive Mirena placement or not after hysteroscopic polypectomy； Be scheduled for a follow-up with TVCD to screen for endometrial polyps recurrence every 6 months.

5Fr Bipolar Electrode vs. Conical Optical 5Fr Fibers for Dual Wave-length Diode Laser for Hysteroscopic Polypectomy

The primary objective of this study is to compare the performance of two different surgical instruments, the 5 Fr bipolar electrode and the 5 Fr angled conical optical fiber for dual wavelength diode laser, in performing hysteroscopic polypectomy in an outpatient setting.