Clinical Research Directory

Combined Effects of Proprioceptive Neuromuscular Facilitation (PNF) and Neural Mobilization on Improving Facial Symmetry in Patients With Bells Palsy

Bell's palsy is an acute,unilateral facial paresis that significantly affects patient's facial symmetry,motor function and quality of life.The primary goal of this randomized controlled trial is to determine if integrating the targeted neural mobilization with proprioceptive neuromuscular facilitation improves facial symmetry and motor function more effectively than using pnf alone.participants allocated to either experimental group receiving neural mobilization and pnf or control group receiving pnf alone.after approval from ERC FUSH, participants are assessed using housebrackman scale and sunnybrook facial grading system(scales to asses the degree of severity of facial paralysis) at first and fourth week of intervention application.data will be analysed using spss v.22.

Asymmetry Index From Photogrammetric Analysis

We propose a transversal observational study, to be performed on three-dimensional images acquired through photogrammetry of patients who will undergo orthodontic treatments. The aim of our research consists in the evaluation of facial asymmetry through a graph built on three degrees of Asymmetry Index (symmetry, slight asymmetry, asymmetry) in an Italian population that meets the criteria of absence of craniofacial deformities and that has not undergone surgery or orthodontic treatment. For the analysis, images acquired via photogrammetry are used, then analyzed with the Geomagic Control 2014 program (64 bit).

Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.

This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects. The study will include patients presenting with congenital, traumatic, or post-surgical facial deformities requiring reconstructive intervention. Eligible participants will undergo preoperative clinical assessment and radiological imaging to design customized implants using computer-aided design (CAD) and 3D printing technology. The implants will be fabricated from medical-grade titanium and surgically placed according to standardized maxillofacial reconstructive protocols. Postoperative follow-up will assess functional outcomes, implant stability, complication rates, and aesthetic improvement over a defined observation period. Outcome evaluation will include clinical examination and patient-reported satisfaction measures. The objective of this study is to determine whether patient-specific 3D-printed titanium implants provide reliable functional restoration and improved aesthetic outcomes in facial reconstruction compared to conventional reconstructive techniques.

Effects of Myofascial Release Therapy on Body Posture and Facial Symmetry

This randomized controlled study aims to investigate the effects of myofascial release therapy on body posture and facial symmetry in healthy individuals. Postural disorders and fascial tension may lead to biomechanical alterations not only in the musculoskeletal system but also in facial soft tissues and symmetry. Myofascial release techniques are widely used in physiotherapy to improve fascial mobility, reduce tissue tension, and support postural alignment. However, the potential effects of these interventions on facial symmetry have not been sufficiently investigated. A total of 60 healthy participants will be included in the study and randomly assigned to either an intervention group or a control group. Participants in the intervention group will receive myofascial release therapy twice weekly for 6 weeks, while the control group will not receive any physical intervention during the same period. Body posture and facial symmetry assessments will be performed at baseline and after the intervention period. Postural assessment will be conducted using the PostureScreen Mobile application through standardized anterior, posterior, and lateral photographs. Facial symmetry will be evaluated using anthropometric facial landmarks identified on standardized facial photographs. Directional asymmetry scores, linear measurements, proportional analyses, and angular measurements will be calculated. The study is expected to provide evidence regarding the relationship between fascial interventions, postural alignment, and facial symmetry, and may contribute to the development of new physiotherapy approaches targeting fascial and postural dysfunctions.

Exploring Optimal Photographic Parameters for Standardized Facial Aesthetics Analysis

The main objective of this research is to identify the focal length that allows the most accurate and reproducible 2D assessment of facial aesthetics, without introducing significant distortion. Ultimately, this will enable the establishment of a standardized photography protocol for maxillofacial and aesthetic surgery, facilitating harmonized pre- and post-operative assessments and improving communication between healthcare providers and patients.

Assessment of the Accuracy of Patient Specific Plates for Correction of Maxillary Cant in Facial Asymmetry

The goal of this clinical trial is to learn how accurate patient-specific plates (PSPs) are for correcting a tilted upper jaw (maxillary cant) in people with facial asymmetry. The main questions it aims to answer are: * How closely does the actual surgery match the virtual surgical plan? * How satisfied are participants with how they look after surgery? Researchers will compare the surgery results using PSPs to the original 3D virtual plan to see how well they match. Participants will: * Have a CT scan and 3D virtual surgery planning * Get custom-made plates designed to fit their upper jaw * Undergo surgery to correct the tilt of the upper jaw * Be followed for up to 6 months to check healing and results

The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry

Facial asymmetry, the degree to which the two sides of the face differ in size, shape, or the arrangement of features, is a near-universal human characteristic. The intricate network of facial muscles plays a crucial role in both the static structure and the dynamic expressions of the face. The continuous pull and action of facial muscles can influence the development and positioning of underlying soft tissues and even, over extended periods, potentially impact skeletal structures.