Clinical Research Directory

Comparison of KIRA Hydrating Treatment and Jet Peel for Facial Skin Hydration

This study compared the efficacy and tolerability of two non-invasive facial treatment systems for improving skin hydration: a hydroabrasion-jet system (KIRA) and a conventional high-pressure jet system (JET PEEL). Twenty-three women aged 30-65 years underwent three treatment sessions using an intraindividual split-face design, with KIRA applied to the left side of the face and JET PEEL to the right side. Skin hydration was assessed by corneometry at baseline, 48 hours after the first treatment, and before the second and third treatments, with the measurement before the third treatment defined as the primary endpoint. Additional exploratory assessments included multispectral skin imaging, participant-reported treatment experience and preference, and a Day-21 follow-up. The study aimed to determine whether enhanced epidermal preparation using hydroabrasion combined with lower-pressure jet infusion could achieve hydration outcomes comparable to those obtained with a conventional higher-pressure jet system.