Clinical Research Directory

Prognostic Impact of Neopterin on Resumption of Walking After a Fracture of the Upper Neck of the Femur in the Elderly

Society faces a major challenge with the management of the health and socio-economic burden caused by acute physical stress in the older population (\>75 years). In particular, hip fracture (HF) represents a major health care preoccupation, affecting 1.6 M patients worldwide, resulting in a significant drop of life quality and autonomy. Nowadays, this trauma is still associated with a poor outcome of 20-30% one-year mortality in the elderly. This emphasizes the value of assessing biological factors that may predict clinical outcome after HF. The preliminary work pinpoints a central role of neopterin in loss of autonomy and death. Using HF as an acute stress model that accelerates the progressive course of aging, the aim is to validate neopterin as a predictive biomarker of pernicious clinical outcomes.

Medial Enhancement Technique for the Treatment of Old Femoral Neck Fractures

A prospective, multi-center, randomized controlled study was conducted to validate the safety and effectiveness of employing the medial augmentation technique (incorporating the dynamic condylar screw and medial support plate) supplemented with bone grafting for the treatment of old femoral neck fractures.

Orthopedic Intelligent Navigation System in the Treatment of Fresh Femoral Neck Fractures

The goal of this clinical trial is to verify the safety and effectiveness of orthopaedic surgical navigation system in the treatment of fresh femoral neck fractures. Participants will: * Take three cannulated compression screws by navigation system or by traditional method to treat femoral neck fractures. * Visit the clinic 1, 3, 6, 12 months after surgery for checkups and tests.