Clinical Research Directory
Browse clinical research sites, groups, and studies.
4 clinical studies listed.
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Tundra lists 4 GVHD, Chronic clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT06279676
Improvement of Women's Health After Allogeneic Stem Cell Transplantation
The aim of this prospective research project is to better understand vulvovaginal cGVHD to improve care of allografted women. The expected outcomes include better knowledge of the incidence and manifestations of vulvovaginal cGVHD, risk factors, response to treatments and impact on sexual health of allotransplanted female patients. The knowledge acquired will allow transplant clinicians to make more precise recommendations for gynecological management of future allografted women.
Gender: FEMALE
Ages: 18 Years - Any
Updated: 2026-03-18
1 state
NCT07314892
Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).
This prospective observational study evaluates the association between psychiatric status, GvHD-related symptom severity, and health-related quality of life in patients with graft-versus-host disease. Standardized and validated assessment tools, including the Lee Symptom Scale, will be used to collect psychiatric, clinical, and demographic data.
Gender: All
Ages: 18 Years - 75 Years
Updated: 2026-01-02
1 state
NCT06169722
TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD))
1. Phase Ib study stage: Primary objective: To evaluate the efficacy and safety Secondary objectives: To evaluate the population pharmacokinetic characteristics 2. Phase II study stage: Primary objective: To evaluate the efficacy Secondary objectives: To evaluate the safety
Gender: All
Ages: 18 Years - 75 Years
Updated: 2025-09-26
1 state
NCT06462365
Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)
The purpose of this Phase 1, first in human open-label study is to assess the safety and tolerability of TRX-103 in patients with hematological malignancies undergoing HLA-mismatched related or unrelated hematopoietic stem cell transplantation (HSCT). It is anticipated that up to 36 Subjects will be enrolled during a 18-24 month enrollment period. TRX-103 will be infused one time post HSCT.
Gender: All
Ages: 18 Years - Any
Updated: 2025-04-15
5 states