Clinical Research Directory

Heart Rate Variability and Early Cytokine Profile in Pediatric Adenotonsillectomy

This prospective observational cohort study will assess whether perioperative short-term heart rate variability (HRV) indices and early inflammatory cytokine levels are associated with respiratory and cardiac adverse events in children undergoing elective adenoidectomy, tonsillectomy, or adenotonsillectomy under general anesthesia. HRV will be recorded noninvasively from 30 minutes before surgery until discharge from the post-anesthesia care unit. Serum cytokines will be measured from 3 mL of residual blood obtained after induction of anesthesia. The study aims to identify perioperative physiologic markers associated with a lower or higher risk of adverse events, thereby supporting safer anesthetic planning.

Research Proposal on the Effects of Different Altitude Conditions on Human Time Perception.

The aim of this observational study is to investigate human time perception ability for different time intervals (540 ms, 1080 ms, 1620 ms, 2160 ms, 5 s, 10 s, 20 s, 50 s) under conditions of varying altitudes (500 m, 1000 m, 1500 m, 2000 m, 2500 m, 3000 m). Specifically, a hypobaric chamber will be used to simulate the aforementioned altitudes, and temporal reproduction tasks with different standard durations will be conducted at each altitude. The time difference between the actual perceived duration and the target duration will be calculated to assess the level of time perception ability-with a smaller difference indicating stronger time perception ability. At each altitude, participants' heart rate (HR) and oxygen saturation (SpO₂) will also be monitored to explore the correlation between physiological status and time perception ability under different altitude conditions.