Clinical Research Directory

Robot-Assisted Mirror Therapy in the Rehabilitation of Hemiparetic Cerebral Palsy

The goal of this clinical trial is to learn whether robot-assisted mirror therapy improves upper extremity function in children with spastic hemiparetic cerebral palsy. The study will also compare the effects of robot-assisted mirror therapy with those of conventional mirror therapy. The main questions this study aims to answer are: * Does robot-assisted mirror therapy improve spasticity, grip strength, selective motor control, hand skills, bimanual performance, participation in activities of daily living, and quality of life? * Does robot-assisted mirror therapy improve upper extremity function more than conventional mirror therapy? Researchers will compare robot-assisted mirror therapy combined with neurodevelopmental treatment with conventional mirror therapy combined with neurodevelopmental treatment. Participants will: * Receive individualized neurodevelopmental treatment for 6 weeks. * Complete a 2-week interval after neurodevelopmental treatment. * Be randomly assigned to either the robot-assisted mirror therapy group or the conventional mirror therapy group. * Receive robot-assisted mirror therapy or conventional mirror therapy twice a week for 6 weeks. * Complete assessments before neurodevelopmental treatment, after neurodevelopmental treatment, before the study intervention, and after the intervention. Researchers will evaluate upper extremity function, spasticity, grip strength, selective motor control, hand skills, bimanual performance, participation in activities of daily living, and quality of life using standardized clinical assessment tools.

Effect of Reciprocal Electrical Stimulation on Balance and Quality of Life in Hemiparetic CP

to investigate the effect of the reciprocal neuromuscular electrical stimulation on balance and quality of life in hemiparetic children

Using Neurotechology to Help Children With Physical Disability Due to Cerebral Palsy

Hemiparetic cerebral palsy is a condition in which one side of a child's body becomes weak due to brain injury occurring around birth, often caused by stroke. Weakness on the affected side reduces the ability to use the involved hand and arm, limiting everyday activities such as dressing, eating, and playing. Few effective treatments currently exist, especially for children with severe weakness. The study described here examines a new therapy that combines Brain-Computer Interface (BCI) technology with Functional Electrical Stimulation (FES). BCI technology uses brain signals to control external devices; in this therapy, brain signals activate muscles through electrical stimulation. When a child imagines wrist movement, the system detects the associated brain activity and delivers electrical stimulation to generate actual movement. Such paired activity supports neural rewiring and strengthens connections between the brain and muscles, leading to improved arm function. Previous research demonstrates strong benefits of BCI-FES for adults after stroke, but minimal testing has been conducted with children. The current study will evaluate whether BCI-FES improves arm and hand function in children aged 12 to 17 with hemiparetic cerebral palsy. Participants will complete 15 to 20 sessions over a two-month period while wearing a cap that records brain signals. During each session, the system provides muscle stimulation and visual feedback through animated hand movements. Outcome measures will include performance of daily tasks, hand dexterity, muscle activity, and the presence of any adverse effects. The overarching goal is to create a fun, engaging, and effective therapy that supports recovery of hand use and greater independence. Successful results could guide larger studies and inspire new technology-based treatments that enhance quality of life for children with cerebral palsy.

Effects Obtained at Manual Function After Applying Anodic Transcranial Direct Current Stimulation (tCDS) in Children With Spastic Hemiparetic Cerebral Palsy

Spastic Hemiparetic Cerebral Palsy (SHCP) uses to limit the manual function. Using anodic transcranial direct current stimulation, it is possible to activate certain cerebral areas depending on where the electrodes are. This study will use this kind of stimulation on the contralateral primary motor cortex of the affected upper limb and analyze the effects.