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Immunosuppression-related Infectious Disease

Tundra lists 1 Immunosuppression-related Infectious Disease clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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RECRUITING

NCT04526431

Tacrolimus Pharmacokinetic Subpopulations

This prospective study will investigate the concentrations of tacrolimus metabolites (M-I and M-III) over the four first years post-transplantation. A differential metabolism might result in different metabolites' concentration and explain a kidney survival difference between "high rate metabolism" (defined as a concentration/dose ratio, C/D ratio, lower than 1.04 µg/l/mg) and other patients. The primary endpoint is therefore to compare tacrolimus metabolites' concentrations with respect to the group, either \< or \>= 1.04 µg/l/mg, in order to detect differences in tacrolimus metabolization between these groups.

Gender: All

Ages: 18 Years - Any

Updated: 2021-02-10

1 state

Kidney Transplant Failure and Rejection

Immunosuppression-related Infectious Disease